Abstract
Pyrrole is one of the main five membered heterocyclic systems reported for its various chemotherapeutic activities. Subsequently, pyrroles have been highlighted as the important biologically active scaffolds. This review focuses on the synthesis, reactions and pharmacological activity associated with pyrroles, and its derivatives. Microwave-assisted reactions are also covered to understand green chemistry aspects of pyrrole and its derivatives. Various pharmacological applications are discussed critically to assess the importance of the compounds.
Keywords: Pyrroles, Microwave synthesis, Applications.
Current Organic Chemistry
Title:Pyrrole: Chemical Synthesis, Microwave Assisted Synthesis, Reactions and Applications: A Review
Volume: 17 Issue: 20
Author(s): Shrinivas D. Joshi, Uttam A. More, Venkatrao H. Kulkarni and Tejraj M. Aminabhavi
Affiliation:
Keywords: Pyrroles, Microwave synthesis, Applications.
Abstract: Pyrrole is one of the main five membered heterocyclic systems reported for its various chemotherapeutic activities. Subsequently, pyrroles have been highlighted as the important biologically active scaffolds. This review focuses on the synthesis, reactions and pharmacological activity associated with pyrroles, and its derivatives. Microwave-assisted reactions are also covered to understand green chemistry aspects of pyrrole and its derivatives. Various pharmacological applications are discussed critically to assess the importance of the compounds.
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Cite this article as:
Joshi D. Shrinivas, More A. Uttam, Kulkarni H. Venkatrao and Aminabhavi M. Tejraj, Pyrrole: Chemical Synthesis, Microwave Assisted Synthesis, Reactions and Applications: A Review, Current Organic Chemistry 2013; 17 (20) . https://dx.doi.org/10.2174/13852728113179990040
DOI https://dx.doi.org/10.2174/13852728113179990040 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
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