Abstract
Pyrrole is one of the main five membered heterocyclic systems reported for its various chemotherapeutic activities. Subsequently, pyrroles have been highlighted as the important biologically active scaffolds. This review focuses on the synthesis, reactions and pharmacological activity associated with pyrroles, and its derivatives. Microwave-assisted reactions are also covered to understand green chemistry aspects of pyrrole and its derivatives. Various pharmacological applications are discussed critically to assess the importance of the compounds.
Keywords: Pyrroles, Microwave synthesis, Applications.
Current Organic Chemistry
Title:Pyrrole: Chemical Synthesis, Microwave Assisted Synthesis, Reactions and Applications: A Review
Volume: 17 Issue: 20
Author(s): Shrinivas D. Joshi, Uttam A. More, Venkatrao H. Kulkarni and Tejraj M. Aminabhavi
Affiliation:
Keywords: Pyrroles, Microwave synthesis, Applications.
Abstract: Pyrrole is one of the main five membered heterocyclic systems reported for its various chemotherapeutic activities. Subsequently, pyrroles have been highlighted as the important biologically active scaffolds. This review focuses on the synthesis, reactions and pharmacological activity associated with pyrroles, and its derivatives. Microwave-assisted reactions are also covered to understand green chemistry aspects of pyrrole and its derivatives. Various pharmacological applications are discussed critically to assess the importance of the compounds.
Export Options
About this article
Cite this article as:
Joshi D. Shrinivas, More A. Uttam, Kulkarni H. Venkatrao and Aminabhavi M. Tejraj, Pyrrole: Chemical Synthesis, Microwave Assisted Synthesis, Reactions and Applications: A Review, Current Organic Chemistry 2013; 17 (20) . https://dx.doi.org/10.2174/13852728113179990040
DOI https://dx.doi.org/10.2174/13852728113179990040 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Calcium Homeostasis Following Traumatic Neuronal Injury
Current Neurovascular Research Reactive Astrocytes as Potential Manipulation Targets in Novel Cell Replacement Therapy of Parkinsons Disease
Current Drug Targets Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons
Current Drug Targets The Interaction of Zinc Oxide/Green Tea Extract Complex Nanoparticles and its Effect on Monosodium Glutamate Toxicity in Liver of Rats
Current Pharmaceutical Biotechnology Preparation of Tiagabine HCl/2-HPβCD Complex Pellets by Extrusion-Spheronization Using Glycerol Monostearate as Pellet-Aid
Letters in Drug Design & Discovery Involvement of Potassium and Chloride Channels and Other Transporters in Volume Regulation by Spermatozoa
Current Pharmaceutical Design Sugar-Borate Esters – Potential Chemical Agents in Prostate Cancer Chemoprevention
Anti-Cancer Agents in Medicinal Chemistry Conotoxin Superfamily Prediction Using Diffusion Maps Dimensionality Reduction and Subspace Classifier
Current Protein & Peptide Science Feature Extraction and Classification of Epilepsy in Different Seizure Types: A Survey
Current Medical Imaging Current Methods in the Automatic Tissue Segmentation of 3D Magnetic Resonance Brain Images
Current Medical Imaging Hybrid SPECT/CT Imaging in Neurology
Current Radiopharmaceuticals Translocator Protein Ligands as Promising Therapeutic Tools for Anxiety Disorders
Current Medicinal Chemistry Editorial [Hot Topic: Recent Developments in the Drug Discovery of Epilepsy (Guest Editor: Waquar Ahsan)]
Current Topics in Medicinal Chemistry The Molecular Basis of Conantokin Antagonism of NMDA Receptor Function
Current Drug Targets Chinese Herbal Medicine Interventions in Neurological Disorder Therapeutics by Regulating Glutamate Signaling
Current Neuropharmacology Synaptic Plasticity, Metaplasticity and Depression
Current Neuropharmacology PDZ Domain-mediated Protein Interactions: Therapeutic Targets in Neurological Disorders
Current Medicinal Chemistry Commentary: Participation of Sox-1 Expression and Signaling of β-Catenin in the Pathophysiology of Generalized Seizures in Cerebellum of Rat
CNS & Neurological Disorders - Drug Targets Simple and Fast Gas-chromatography Mass Spectrometry Assay to Assess Delta 9-Tetrahydrocannabinol and Cannabidiol in Dogs Treated with Medical Cannabis for Canine Epilepsy
Current Pharmaceutical Biotechnology Medications not Intended for Treatment of Dyslipidemias and with a Variable Effect on Lipids
Current Pharmaceutical Design