Biomaterials and Scaffolds in Bone and Musculoskeletal Engineering

Title:Biomaterials and Scaffolds in Bone and Musculoskeletal Engineering

Volume: 8 Issue: 3

Author(s): Dennis Kosuge, Wasim S. Khan, Behrooz Haddad and David Marsh

Affiliation:

Keywords: Biomaterials, orthopaedics, scaffolds, tissue engineering

Abstract: In orthopaedic tissue engineering, scaffolds may be viewed as a substitute for the extra-cellular matrix. Factors that contribute to an ideal scaffold include strength, degradation rate, porosity, surface property and immune response. Scaffolds may be composed of natural or synthetic polymers, each with its advantages and disadvantages. Composite scaffolds are utilised to alleviate the inherent issues with natural polymers whilst maintaining its benefits as well. This article reviews biomaterials and scaffolds in orthopaedic tissue engineering and covers clinical applications of scaffolds with particular emphasis on bone and cartilage tissue engineering.

Cite this article as:

Kosuge Dennis, S. Khan Wasim, Haddad Behrooz and Marsh David, Biomaterials and Scaffolds in Bone and Musculoskeletal Engineering, Current Stem Cell Research & Therapy 2013; 8 (3) . https://dx.doi.org/10.2174/1574888X11308030002