Abstract
An ideal drug must be absolutely inert in normal conditions, providing release of active compounds only in diseased areas. Nanoengineered polymeric capsules have required features. We describe here basic methods for the fabrication of such containers and give some particular examples of their use when the drug release is triggered by the presence of the disease itself or by the soft external action, with no side effects on the adjacent tissues.
Keywords: Ideal drug carrier, Layer-by-Layer electrostatic self-assembly, Polyelectrolyte capsules, Targeted drug delivery, Triggered drug release, Bacteriorhodopsin (BR), UV irradiation of azobenzene, Biocompatibilty, Confocal laser scanning microscopy (CLSM), Nanoengineered Polymeric Capsules
Current Organic Chemistry
Title:Smart Nanoengineered Polymeric Capsules as Ideal Pharmaceutical Carriers
Volume: 17 Issue: 1
Author(s): Laura Pastorino, Svetlana Erokhina and Victor Erokhin
Affiliation:
Keywords: Ideal drug carrier, Layer-by-Layer electrostatic self-assembly, Polyelectrolyte capsules, Targeted drug delivery, Triggered drug release, Bacteriorhodopsin (BR), UV irradiation of azobenzene, Biocompatibilty, Confocal laser scanning microscopy (CLSM), Nanoengineered Polymeric Capsules
Abstract: An ideal drug must be absolutely inert in normal conditions, providing release of active compounds only in diseased areas. Nanoengineered polymeric capsules have required features. We describe here basic methods for the fabrication of such containers and give some particular examples of their use when the drug release is triggered by the presence of the disease itself or by the soft external action, with no side effects on the adjacent tissues.
Export Options
About this article
Cite this article as:
Pastorino Laura, Erokhina Svetlana and Erokhin Victor, Smart Nanoengineered Polymeric Capsules as Ideal Pharmaceutical Carriers, Current Organic Chemistry 2013; 17 (1) . https://dx.doi.org/10.2174/138527213805289088
DOI https://dx.doi.org/10.2174/138527213805289088 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators
Anti-Cancer Agents in Medicinal Chemistry Wnt1 Inducible Signaling Pathway Protein 1 (WISP1) Blocks Neurodegeneration through Phosphoinositide 3 Kinase/Akt1 and Apoptotic Mitochondrial Signaling Involving Bad, Bax, Bim, and Bcl-xL
Current Neurovascular Research Modulators of the microRNA Biogenesis Pathway via Arrayed Lentiviral Enabled RNAi Screening for Drug and Biomarker Discovery
Combinatorial Chemistry & High Throughput Screening Detection of Predictive Markers for Therapeutic Stratification of Salivary Glands Tumors
Current Drug Targets Template Dependent Human DNA Polymerases
Current Topics in Medicinal Chemistry Expression Profile of Genes Associated with the Proteins Degradation Pathways in Colorectal adenocarcinoma
Current Pharmaceutical Biotechnology Star Graphs of Protein Sequences and Proteome Mass Spectra in Cancer Prediction
Current Proteomics Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications
Current Cancer Drug Targets Rational Drug Design of Antineoplastic Agents Using 3D-QSAR, Cheminformatic, and Virtual Screening Approaches
Current Medicinal Chemistry Developments of Polo-like Kinase 1 (Plk1) Inhibitors as Anti-Cancer Agents
Mini-Reviews in Medicinal Chemistry Recent Developments in Computer Aided Diagnosis for Lung Nodule Detection from CT images: A Review
Current Medical Imaging Potassium Channels: Novel Emerging Biomarkers and Targets for Therapy in Cancer
Recent Patents on Anti-Cancer Drug Discovery Role of Human and Mouse HspB1 in Metastasis
Current Molecular Medicine Phytochemicals Resveratrol and Sulforaphane as Potential Agents for Enhancing the Anti-Tumor Activities of Conventional Cancer Therapies
Current Pharmaceutical Biotechnology Discovery of New Biomarkers of Cancer Using Proteomics Technology
Current Cancer Therapy Reviews Antiproliferative Activity of Cobra Venom Cytotoxins
Current Topics in Medicinal Chemistry Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals
Current Drug Targets The Potential of Natural Products as Effective Treatments for Allergic Inflammation: Implications for Allergic Rhinitis
Current Topics in Medicinal Chemistry Mechanisms of Neutrophil-mediated Disease: Innovative Therapeutic Interventions
Current Pharmaceutical Design RAS/RAF/MEK Inhibitors in Oncology
Current Medicinal Chemistry