Abstract
Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.
Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor
Current Medicinal Chemistry
Title:Dendrimers in Photodynamic Therapy
Volume: 19 Issue: 29
Author(s): B. Klajnert, M. Rozanek and M. Bryszewska
Affiliation:
Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor
Abstract: Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.
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Cite this article as:
Klajnert B., Rozanek M. and Bryszewska M., Dendrimers in Photodynamic Therapy, Current Medicinal Chemistry 2012; 19 (29) . https://dx.doi.org/10.2174/0929867311209024903
DOI https://dx.doi.org/10.2174/0929867311209024903 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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