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Current Gene Therapy

Editor-in-Chief

ISSN (Print): 1566-5232
ISSN (Online): 1875-5631

Adenovirus Vectors and Subviral Particles for Protein and Peptide Delivery

Author(s): Matthias W. Kron and Florian Kreppel

Volume 12, Issue 5, 2012

Page: [362 - 373] Pages: 12

DOI: 10.2174/156652312802762563

Price: $65

Abstract

Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition, adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications ranging from vaccination to gene therapy.

Keywords: Protein delivery, adenovirus vector, adenovirus subviral particles, peptide delivery, gene transfer vectors, vector capsids, epidermal growth factor, endosomal


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