Abstract
Eaton’s reagent efficiently catalyzed the Claisen-Schmidt condensation reaction of aryl aldehydes with aromatic and cyclic ketones under solvent free microwave irradiation conditions to afford mono and bis-chalcone derivatives. The present approach offers several advantages such as shorter reaction times, cleaner reactions, good yields, inexpensive reagent and mild reaction conditions.
Keywords: Aromatic aldehydes, aromatic ketone, chalcones, cyclic ketone, eaton’s reagent, solvent-free, fused pyridines, thiazines, pyrimidines, iodine
Letters in Organic Chemistry
Title:Revisit: Eaton’s Reagent Catalyzed Synthesis of Mono and Bis-Chalcone Derivatives
Volume: 9 Issue: 7
Author(s): Shrikrishna. D. Tupare, Santosh V. Nalage, Sharad R. Bobe, Shivshankar N. Hallale, Sheshanath V. Bhosale, Sanjay K. Vyawahare, Satish A. Dake, Sidhanath V. Bhosale and Rajendra P. Pawar
Affiliation:
Keywords: Aromatic aldehydes, aromatic ketone, chalcones, cyclic ketone, eaton’s reagent, solvent-free, fused pyridines, thiazines, pyrimidines, iodine
Abstract: Eaton’s reagent efficiently catalyzed the Claisen-Schmidt condensation reaction of aryl aldehydes with aromatic and cyclic ketones under solvent free microwave irradiation conditions to afford mono and bis-chalcone derivatives. The present approach offers several advantages such as shorter reaction times, cleaner reactions, good yields, inexpensive reagent and mild reaction conditions.
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D. Tupare Shrikrishna., V. Nalage Santosh, R. Bobe Sharad, N. Hallale Shivshankar, V. Bhosale Sheshanath, K. Vyawahare Sanjay, A. Dake Satish, V. Bhosale Sidhanath and P. Pawar Rajendra, Revisit: Eaton’s Reagent Catalyzed Synthesis of Mono and Bis-Chalcone Derivatives, Letters in Organic Chemistry 2012; 9 (7) . https://dx.doi.org/10.2174/157017812802139627
DOI https://dx.doi.org/10.2174/157017812802139627 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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