Abstract
The objective of the present chapter is to discuss the identification of cancer stem cells (CSC) in pancreatic ductal adenocarcinomas (PDAs) and hepatocellular carcinoma (HCC) and to briefly overview the current therapies targeting this cell population. The reason to restrict the discussion to these particular cancer types is that both are described by a poor prognosis and resistance to conventional therapies. Therefore, CSC may be an important hint in improving the therapeutic approach in both instances. Due to the capacity of CSC to escape chemo and radiotherapy, novel means of approaching these cells are necessary in order to improve outcome therapeutically.
Keywords: Cancer stem cell, Cell surface marker, Drug resistance, Hepatic cellular carcinoma, Liver cancer, Metastases, Pancreatic cancer.
Related Books
Andrology: Current and Future Developments
Male Infertility: An Integrative Manual of Western and Chinese Medicine
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Awake Thoracic Surgery
The Anatomical Foundations of Regional Anesthesia and Acute Pain Medicine Macroanatomy Microanatomy Sonoanatomy Functional anatomy
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents