Malignant Pleural Mesothelioma: Present Status and Future Directions

Value of Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma

Author(s): Andrea S. Wolf and Raja H. Flores

Pp: 413-427 (15)

DOI: 10.2174/9781681081946116010032

* (Excluding Mailing and Handling)

Abstract

Although there is lack of consensus regarding the “standard of care” for malignant pleural mesothelioma, surgery-based multimodality therapy has demonstrated long-term survivors in multiple retrospective and prospective trials. The authors advocate radical or extended pleurectomy/decortication when possible, but for patients with adequate cardiopulmonary function in whom disease is resectable only by extrapleural pneumonectomy, this operation now has a long track record of safety and serves a critical role in the treatment of this aggressive disease.


Keywords: Chemotherapy, Extrapleural pneumonectomy, thoracic surgery.

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