Emerging Approaches to Tackle Neglected Diseases: From Molecule to End Product

Emerging Therapy for Dengue

Author(s): Inderjeet Verma*, Meenakshi Dhanawat, Garima Malik, Arti Saini and Poonam Bharti

Pp: 48-65 (18)

DOI: 10.2174/9789815196863124010006

* (Excluding Mailing and Handling)

Abstract

There are over 60 countries where dengue fever is endemic, and 2.5 billion people could get sick from it. An RNA virus belonging to the Flaviviridae family that causes acute viral disease dengue is transmitted by Aedes mosquitoes. The presenting signs may be asymptomatic fever with severe implications such as hemorrhagic fever and shock. The most common symptoms are acute-onset high fever, cutaneous rash, hemorrhagic episodes, myalgia and circulatory shock. Although oral symptoms are seldom the primary presenting sign of dengue infection, they may occur in certain cases. Early and precise diagnosis is necessary for lowering mortality. Dengue virus infections are typically self-limiting, but in tropical and subtropical countries, dengue infection has become a public health threat. A detailed explanation of dengue virus infections, clinical symptoms, diagnostic techniques, and preventative measures are all included in this book chapter.

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