Abstract
Chronic pain is a major cause of physical disability, poor mental health, and
decreased quality of life [1,2]. The burden of chronic pain is reflected in increased
medical care utilization and consequently increased healthcare costs, which are
estimated at an astounding $560 billion per year [3]. CDC estimates from 2019 reveal
that while 20.4% of adults in the USA live with chronic pain, the prevalence increases
with advancing age [4]. 30.8% of people aged 65 years and above had chronic pain
while 11.8% of them had high-impact chronic pain, which is defined as pain that
causes significant restriction of self-care, social and work-related activities [5]. The
impact of chronic pain is more severe in the elderly; older adults report poorer physical
health and disability in comparison to younger adults [6-8]. Chronic pain in the elderly
is also associated with poorer sleep, cognitive decline, dementia, and death [9-13].
With the projected increase in the elderly population in the US every year, the burden
of chronic pain is only expected to increase. This chapter outlines the physiologic and
pharmacologic changes that happen with ageing, the major causes of chronic pain in
the elderly, as well as the myriad of treatment options available with a focus on
pharmacotherapy, behavioral and alternative therapies, and interventional pain
therapies. The focus of treatment is not only targeted towards reducing pain but special
considerations should be made to minimize the cognitive effects of polypharmacy in
light of multiple comorbidities and promote mental well-being and functional
independence [14].