Abstract
Glycyrrhiza glabra belongs to the family Fabaceae and is commonly called
licorice. It is an important medicinal plant in Europe, China, and the Mediterranean.
The plant's therapeutic value is also mentioned in Ayurveda and Siddha. Licorice is
cultivated for commercial purposes in many parts of the world because of its economic
value and demand. It is used as a flavoring agent in juices, candies, soft drinks, and
beverages because of its characteristic taste and smell. In addition, it is regarded as a
sweetener and thirst quencher. Licorice contains phytochemicals, and the most
abundant compounds are glycyrrhizic acid, anethole, liquiritigenin, isoliquiritin,
pinocembrin, and licoflavanone. The plant is a good source of antioxidants and exhibits
anti-inflammatory, antimicrobial, antiviral, anti-diabetic, and anti-cancer activity. Even
though it has many health-benefiting features, consuming high amounts of licorice can
lead to hypertension, hypokalemia, and congestive heart failure. Due to its high
demand, good medicinal value, and poorly developed cultivation strategy, researchers
are focusing on different aspects of the in vitro propagation of the plant. Studies have
revealed that micropropagation of licorice has improved the level of secondary
metabolites and high antioxidant properties. Thus, this chapter focuses on the
propagation method of licorice, primarily focusing on micropropagation. Moreover, it
also highlights the phytochemistry and important pharmacological activity of
Glycyrrhiza glabra.