Genome Editing in Bacteria (Part 1)

L. Plantarum of Vegetable Origin - Genome Editing and Applications

Author(s): Sudeepa E. S.* and A. Sajna

Pp: 140-155 (16)

DOI: 10.2174/9789815165678124010010

* (Excluding Mailing and Handling)

Abstract

Lactobacillus plantarum is a widespread, versatile bacterium that plays a vital role in the preservation of innumerable fermented foods. These strains are commonly employed as silage additives and starter cultures of fermented goods. Genome editing could provide an added benefit by improving the fermentation profile and quality, as well as the accompanying therapeutic benefits.

Genome editing of various strains of L. plantarum can be used commercially to produce L-ribulose or succinic acid, direct lactic acid production, and increased ethanol production. L. plantarum strains or recombinant strains can help restore intestinal flora homeostasis, reduce the number of pathogenic organisms, and could even be employed as vaccine carriers. Food products such as raw and fermented vegetables, olives, and cereals inoculated with probiotic microbes have shown encouraging benefits as people now seek non-dairy based probiotics. L. plantarum of vegetable or plant origin, as well as applications of genome edited strains, are discussed in this book chapter.

Related Journals
Related Books
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version180msRequest Duration26MBMemory UsageGET chapter/{id}/{param?}Route
  • warninglog[23:23:09] LOG.warning: Optional parameter $id declared before required parameter $request is implic...
  • Booting (93.92ms)time
  • Application (85.77ms)time
  • 1 x Booting (52.27%)
    93.92ms
    1 x Application (47.73%)
    85.77ms
    12 templates were rendered
    • ebook.chapter_detailschapter_details.blade.php#?blade
    • layouts.chapter_header_sectionchapter_header_section.blade.php#?blade
    • ebook.chapter_top_bannerchapter_top_banner.blade.php#?blade
    • ebook.chapter_bottom_bannerchapter_bottom_banner.blade.php#?blade
    • ebook.ebook_right_bannerebook_right_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET chapter/{id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ChapterController@GetChapterDetails
    namespace
    App\Http\Controllers
    where
    as
    chapter
    file
    app/Http/Controllers/ChapterController.php:1350-1704
    19 statements were executed24.06ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('59274385','',1,1739834589,1739834589) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1739834589
      1.11msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('59274385','/chapter/21516',1,1739834589,1739834589)
      200μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 59274385 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 59274385) limit 1
      13.26msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 59274385
      • 1: 59274385
      • 2: 59274385
      • 3: 59274385
      • 4: 59274385
      • 5: 59274385
      • 6: 59274385
      • 7: 59274385
      • 8: 59274385
      • 9: 59274385
      • 10: 59274385
      • 11: 59274385
      • 12: 59274385
      • 13: 59274385
      • 14: 59274385
      • 15: 59274385
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • select * from `chapter` where `chapter_id` = '21516' limit 1
      350μsalphaeurekaselec_live_10_06_2022ChapterController.php#1406
      Bindings
      • 0: 21516
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1406
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`chapter_id` = '21516' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      720μsalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 21516
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ChapterController.php:1411
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `keywords` where `chapter_id` = '21516'
      290μsalphaeurekaselec_live_10_06_2022ChapterController.php#1415
      Bindings
      • 0: 21516
      Backtrace
      • 15. app/Http/Controllers/ChapterController.php:1415
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select * from `ebook` where `ebook_id` = 1292 limit 1
      280μsalphaeurekaselec_live_10_06_2022ChapterController.php#1430
      Bindings
      • 0: 1292
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1430
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select count(*) as aggregate from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1292) and se.ebook_id!=1292 and v.ebook_status='1'
      1.9msalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 16. app/Models/Subject.php:238
      • 17. app/Http/Controllers/ChapterController.php:1434
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1292) and se.ebook_id!=1292 and v.ebook_status='1' limit 10 offset 0
      820μsalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 14. app/Models/Subject.php:238
      • 15. app/Http/Controllers/ChapterController.php:1434
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as aggregate from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1292)
      480μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 16. app/Models/Subject.php:255
      • 17. app/Http/Controllers/ChapterController.php:1435
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct j.nid as journal_nid,j.title,j.subtitle,j.issn,j.eissn,j.keyword,sj.journal_id,j.image_file_name,j.flyer_link from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1292) limit 10 offset 0
      500μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 14. app/Models/Subject.php:255
      • 15. app/Http/Controllers/ChapterController.php:1435
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `e`.*, `a`.*, `y`.`year`, `e`.`ebook_volume_id` as `ebook_volume_id`, `a`.`ebook_volume_id` as `ebk_vol_id`, `e`.`ebook_id` as `ebk_ebook_id` from `ebook_volume` as `e` left join `author` as `a` on `e`.`ebook_volume_id` = `a`.`ebook_volume_id` left join `year` as `y` on `y`.`id` = `e`.`year_id` where `e`.`ebook_volume_id` = 3661 and `e`.`is_uploaded` = 1
      540μsalphaeurekaselec_live_10_06_2022EbookVolume.php#271
      Bindings
      • 0: 3661
      • 1: 1
      Backtrace
      • 13. app/Models/EbookVolume.php:271
      • 14. app/Http/Controllers/ChapterController.php:1438
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) rcd from `ebook_volume` where `ebook_id` = 1292 and ebook_volume_id <> 3661 limit 1
      310μsalphaeurekaselec_live_10_06_2022EbookVolume.php#999
      Bindings
      • 0: 1292
      Backtrace
      • 14. app/Models/EbookVolume.php:999
      • 15. app/Http/Controllers/ChapterController.php:1462
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '21516' and content_type = 'c' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      340μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1465
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '3661' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      310μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1478
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 59274385 and j.to_ip >=59274385 )) and ((j.from_date <= 1739834589 and j.to_date >= 1739834589 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3661) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 59274385 and j.to_ip >=59274385 )) and ((j.from_date <= 1739834589 and j.to_date >= 1739834589 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3661) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 59274385 and j.to_ip >=59274385 )) and ((j.from_date <= 1739834589 and j.to_date >= 1739834589 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3661)
      670μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1518
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 59274385 and j.to_ip >=59274385 )) and ((j.from_date <= 1739834589 and j.to_date >= 1739834589 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 21516) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 59274385 and j.to_ip >=59274385 )) and ((j.from_date <= 1739834589 and j.to_date >= 1739834589 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 21516) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 59274385 and j.to_ip >=59274385 )) and ((j.from_date <= 1739834589 and j.to_date >= 1739834589 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 21516)
      600μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 3661 and `b`.`banner_from_date` <= 1739834589 and `b`.`banner_to_date` >= 1739834589 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.13msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 3661
      • 3: 1739834589
      • 4: 1739834589
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='eda384be146b4d6b3b13ee9874a94574'
      250μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        pmcfBziDzb4ZLvFaNWeWRejCmRfGAPiSRVCEKL5X
        uc_cart_id
        eda384be146b4d6b3b13ee9874a94574
        _previous
        array:1 [ "url" => "http://alpha.eurekaselect.com/chapter/21516" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/21516
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:9 [ "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6ImxhRENEanJzUmdDSkYwVWdVeDhyOEE9PSIsInZhbHVlIjoiNjJvQ1UzbU5MY0RhNjNISVlKdTJkOGw1bHc1dVlwaTFLVTgwYkQ5VjM5VT0iLCJtYWMiOiIxZTA1ZTY0YjVhM2Q2ZjEzMDg1MDVkZmFkNzY5NWQ2MjZhZGUzMzU0M2Q5Y2JiYTkxOTBmMWI2YjQ2Mzc4YTJjIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6ImxhRENEanJzUmdDSkYwVWdVeDhyOEE9PSIsInZhbHVlIjoiNjJvQ1UzbU5MY0RhNjNISVlKdTJkOGw1bHc1dVlwaTFLVTgwYkQ5VjM5VT0iLCJtYWMiOiIxZTA1ZTY0YjVhM2Q2" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "keep-alive" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Mon, 17 Feb 2025 23:23:09 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6InRDZ0VObUlha1NRWXZwTGJ4R0FZVnc9PSIsInZhbHVlIjoia0xVZ1ZmajVGWEpnejJlcWxUdkpJTkMzWnFndDdvYW43N0xiRUE2dUNoRkNaUmlFaFIwLzJvak9pRXY2dXE3T0pJeTNHdGExRXNWcEppZ0tFb01PaVcxeEtDdGcwTmhOMmJIRXF5QkFtdCtaODRqSDJyb3hpTnhRSzQvZXFudXkiLCJtYWMiOiI1YTUwZTViZjg0NzExMWQ1YTI0YzI3Nzc4ZDc0NjVlODg5Y2Q3MTk2YTEzNDk0YzlhMDkzYTEzN2YxNjI1NWUwIiwidGFnIjoiIn0%3D; expires=Thu, 20 Feb 2025 11:23:09 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6InRDZ0VObUlha1NRWXZwTGJ4R0FZVnc9PSIsInZhbHVlIjoia0xVZ1ZmajVGWEpnejJlcWxUdkpJTkMzWnFndDdvYW43N0xiRUE2dUNoRkNaUmlFaFIwLzJvak9pRXY2dXE3T0pJeTNHd" 1 => "alphaeurekaselectnet_session=eyJpdiI6IloxUEpHd0Y4b1BtODFJc3J3VzZnakE9PSIsInZhbHVlIjoidW5CNktGdjlGMGllQW5FcWJ0djE4d2E1RnhocUZZLytrQ1NNb3Z0RkhHbE9lT0pDZFMzNFJSV013V0VUaWloT0tRdHdmb09qYmx2YTh5aUVwekZPR0loWk1jQmRaTHd1Uk8yK29LZmx2ZFlyNGxYZEZ2YlRoajlocFhGTHRKV1oiLCJtYWMiOiJjYzhkYjYwMjRiYzMxODYyNjFhMTA5MjIyNGRlMTU3NWM3NzdmYmIzNzI3NDM5MmZlMTJkNjg2MWU5Y2M2MmY4IiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6IloxUEpHd0Y4b1BtODFJc3J3VzZnakE9PSIsInZhbHVlIjoidW5CNktGdjlGMGllQW5FcWJ0djE4d2E1RnhocUZZLytrQ1NNb3Z0RkhHbE9lT0pDZFMzNFJSV01" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6InRDZ0VObUlha1NRWXZwTGJ4R0FZVnc9PSIsInZhbHVlIjoia0xVZ1ZmajVGWEpnejJlcWxUdkpJTkMzWnFndDdvYW43N0xiRUE2dUNoRkNaUmlFaFIwLzJvak9pRXY2dXE3T0pJeTNHdGExRXNWcEppZ0tFb01PaVcxeEtDdGcwTmhOMmJIRXF5QkFtdCtaODRqSDJyb3hpTnhRSzQvZXFudXkiLCJtYWMiOiI1YTUwZTViZjg0NzExMWQ1YTI0YzI3Nzc4ZDc0NjVlODg5Y2Q3MTk2YTEzNDk0YzlhMDkzYTEzN2YxNjI1NWUwIiwidGFnIjoiIn0%3D; expires=Thu, 20-Feb-2025 11:23:09 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6InRDZ0VObUlha1NRWXZwTGJ4R0FZVnc9PSIsInZhbHVlIjoia0xVZ1ZmajVGWEpnejJlcWxUdkpJTkMzWnFndDdvYW43N0xiRUE2dUNoRkNaUmlFaFIwLzJvak9pRXY2dXE3T0pJeTNHd" 1 => "alphaeurekaselectnet_session=eyJpdiI6IloxUEpHd0Y4b1BtODFJc3J3VzZnakE9PSIsInZhbHVlIjoidW5CNktGdjlGMGllQW5FcWJ0djE4d2E1RnhocUZZLytrQ1NNb3Z0RkhHbE9lT0pDZFMzNFJSV013V0VUaWloT0tRdHdmb09qYmx2YTh5aUVwekZPR0loWk1jQmRaTHd1Uk8yK29LZmx2ZFlyNGxYZEZ2YlRoajlocFhGTHRKV1oiLCJtYWMiOiJjYzhkYjYwMjRiYzMxODYyNjFhMTA5MjIyNGRlMTU3NWM3NzdmYmIzNzI3NDM5MmZlMTJkNjg2MWU5Y2M2MmY4IiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6IloxUEpHd0Y4b1BtODFJc3J3VzZnakE9PSIsInZhbHVlIjoidW5CNktGdjlGMGllQW5FcWJ0djE4d2E1RnhocUZZLytrQ1NNb3Z0RkhHbE9lT0pDZFMzNFJSV01" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "pmcfBziDzb4ZLvFaNWeWRejCmRfGAPiSRVCEKL5X" "uc_cart_id" => "eda384be146b4d6b3b13ee9874a94574" "_previous" => array:1 [ "url" => "http://alpha.eurekaselect.com/chapter/21516" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-17 23:23:09GET/chapter/21516112192