Genome Editing in Bacteria (Part 1)

L. Plantarum of Vegetable Origin - Genome Editing and Applications

Author(s): Sudeepa E. S.* and A. Sajna

Pp: 140-155 (16)

DOI: 10.2174/9789815165678124010010

* (Excluding Mailing and Handling)

Abstract

Lactobacillus plantarum is a widespread, versatile bacterium that plays a vital role in the preservation of innumerable fermented foods. These strains are commonly employed as silage additives and starter cultures of fermented goods. Genome editing could provide an added benefit by improving the fermentation profile and quality, as well as the accompanying therapeutic benefits.

Genome editing of various strains of L. plantarum can be used commercially to produce L-ribulose or succinic acid, direct lactic acid production, and increased ethanol production. L. plantarum strains or recombinant strains can help restore intestinal flora homeostasis, reduce the number of pathogenic organisms, and could even be employed as vaccine carriers. Food products such as raw and fermented vegetables, olives, and cereals inoculated with probiotic microbes have shown encouraging benefits as people now seek non-dairy based probiotics. L. plantarum of vegetable or plant origin, as well as applications of genome edited strains, are discussed in this book chapter.

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