Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective

Role of Nanoparticular/Nanovesicular Systems as Biosensors

Author(s): Özlem Çoban* and Emine Taşhan

Pp: 317-355 (39)

DOI: 10.2174/9789815179422123080014

* (Excluding Mailing and Handling)

Abstract

Biosensors are analytical apparatus utilized for the qualitative and quantitative detection of various biological or non-biological analytes. Early diagnosis of diseases (cancer, infectious disease), monitoring environmental pollution, and ensuring food safety are very important in terms of individual and public health. Therefore, it is also crucial to detect these markers sensitively and accurately, with cheap and simple methods, especially despite limited resources. Nanoparticles, thanks to their nano size, provide wide areas of biosensing and amplify signals. In most of the works, it was observed that the limit of detection (LOD) value decreased and the selectivity improved in biosensors prepared using nanosystems compared to conventional sensors. In this respect, the results give us hope for the use of nanosystems in biosensors. In this section, the subject of biosensors is briefly mentioned and mainly studies on the use of nanoparticular/nanovesicular systems in the field of biosensors are included.

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