Abstract
Current conventional diabetes mellitus (DM) therapies are inadequate and
have poor patient compliance. Subsequently, it is necessary to explore nanomedicine in
managing diabetes. In recent years, several nanocarrier systems have been proven
effective in various aspects of diabetes treatment, increasing drug stability, overcoming
different biological barriers, and in enhancing bioavailability. Nanomedicine can
potentially improve the therapeutic effect of drug substances to gain the patient’s belief
and impart a greater level of acceptability. In the present scientific spectrum,
nanomedicines promise to provide sustained and targeted delivery with potential
physical stability for a prolonged period, rendering a safe and effective therapy for
diabetes. This chapter comprehensively elaborates on trends in the drug delivery
system in treating diabetes for improved delivery of different classes of antidiabetic
agents compared to contemporary therapies.