Marine Ecosystems: A Unique Source of Valuable Bioactive Compounds

Future Perspectives for Developing Marine Drug Discovery

Author(s): Hassan A.H. Ibrahim * .

Pp: 394-423 (30)

DOI: 10.2174/9789815051995123030014

* (Excluding Mailing and Handling)

Abstract

Many opportunities, from many marine secondary metabolites including some of the most interesting candidate drugs, have to be used for development in marine drug discovery in parallel to the updated technologies, procedures and protocols. The hope and the net result, in such a manner, are related to the acceleration and management of marine drug discovery as an integrated process from obtaining the sampling until the launch of the drug. The recent protocols targeted gene sequencing methods for identifying secondary metabolic pathways to be used in the biosynthesis of marine natural products (MNP) discovered from marine isolates. Afterward, the synthesis processes for replenishing inventories of compounds and analogs is a critical step. Moreover, the cheminformatics and computer screening of MNP for protein targets have been used to some extent. On the other hand, the collaboration allows sharing of knowledge, tools, finances, and administrative processes, therefore increasing the innovation potential of all parties, playing a greater role. Seriously, the future prospects for developing marine drug discovery involve the collection of relevant information and the evaluation of available opportunities to establish goals through government initiatives and finally to invest and market the drug products from marine origin. In the current chapter, the advanced approaches to marine drug discovery will be explained. Furthermore, this chapter will present both collaboration and innovation in marine drug discovery to increase the effectiveness of drug discovery and advance the production process.

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