Medicinal Plants, Phytomedicines and Traditional Herbal Remedies for Drug Discovery and Development against COVID-19

Drug Therapies against Acute Respiratory Distress: A Critical Endpoint of COVID-19

Author(s): Maha M. Salama, Rana M. Merghany, Ahmed Zayed, Mohamed A. Salem and Shahira M. Ezzat * .

Pp: 110-149 (40)

DOI: 10.2174/9789815049510123010007

* (Excluding Mailing and Handling)

Abstract

Pulmonary diseases have been increasing for decades, which are responsible for the high incidence of morbidity and mortality all over the world. Since the year 2019, the world suffers from coronavirus disease 2019 (COVID-19) which is caused by SARS-CoV-2 and it was classified as a pandemic respiratory disease by the World Health Organization (WHO). The problem of this virus is the lack of a medicine or a specific antivirus drug to combat it, so many approaches have been designed to protect the patients from its symptoms and side effect and also to raise the human innate immunity. Consequently, this chapter will provide an overview of herbs and their derived natural products which have anti-inflammatory, immunomodulatory, and anti-microbial activities which might be beneficial for the discovery of structurally-related compounds that can be candidate therapeutics alleviating the symptoms associated with acute respiratory diseases.

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