Abstract
In recent decades, both the growing global resistance to existing antibiotics
and the shortage of new groups of compounds identified have become a public health
concern. In order to solve it, researchers are now focusing their attention on
unconventional sources, including microbes from harsh environments. In this context,
the aim of this study was to determine whether marine sponges have the ability to
inhibit the growth of microorganisms that are terrestrial in origin and pathogenic to
humans. The majority of these chemicals have so far been found in marine
invertebrates, primarily sponges. Marine sponges are a rich source of structurally
specific natural substances, some exhibiting a diverse variety of biological activities.
Also, excellent sponge drug candidates are often overlooked because the sponges are
either rare or difficult to obtain, or both. Sponges have piqued the interest of scientists
who want to learn more about the associated microbial community and the useful
metabolites they produce, which can be used in pharmaceutical and biotechnological
applications. The ecological importance of mutualistic relationships between marine
sponges and their related microbes cannot be overstated. These bioactive compounds
from microbes protect their hosts from a variety of microbial diseases. These results
indicate that the antimicrobial properties of marine sponge extracts may be used as a
complementary or replacement method for treating microbial infections.