Abstract
The intertwined epidemics of obesity and related disorders such as hypertension, insulin resistance, type 2 diabetes, and subsequent cardiovascular disease pose a major public health challenge. To meet this challenge, we must understand the interplay between adipose tissue and the vasculature. Microvascular dysfunction is important not only in the development of obesityrelated target-organ damage, but also in the development of cardiovascular risk factors such as hypertension and insulin resistance. The present chapter examines the role of microvascular dysfunction as an explanation for the associations among obesity, hypertension and impaired insulin-mediated glucose disposal. We also discuss communicative pathways from adipose tissue to the microcirculation.
Keywords: Obesity, hypertension, insulin resistance, microcirculation.
Related Journals
Current Dentistry
Current Traditional Medicine
Adolescent Psychiatry
New Emirates Medical Journal
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued)
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents
Endocrine, Metabolic & Immune Disorders - Drug Targets
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued)
Current Diabetes Reviews
Related Books
Andrology: Current and Future Developments
Male Infertility: An Integrative Manual of Western and Chinese Medicine
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Awake Thoracic Surgery
The Anatomical Foundations of Regional Anesthesia and Acute Pain Medicine Macroanatomy Microanatomy Sonoanatomy Functional anatomy
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents