Colorectal Cancer Diagnosis and Therapeutic Updates

Pathways in Colorectal Cancer

Author(s): Ajay Madrewar*, Kapil Gore and Sankha Bhattacharya

Pp: 71-80 (10)

DOI: 10.2174/9789815040944122010011

* (Excluding Mailing and Handling)

Abstract

Signaling pathways are important tools for regulating cellular life cycles such as growth and replication. Any external influences may cause a disturbance in signaling, causing an uncontrolled division of cells causing cancer. Many receptors such as EGFR are active in signaling for cancer, which can be targeted to show potent anticancer activity.


Keywords: Chromosomal instability, Microsatellite instability, Pathways, Signalling.

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