Immunotherapy of Sepsis

Sepsis is a clinical condition that occurs due to dysregulated fundamental

host reaction to an infection, resulting in organ dysfunction. Proinflammatory

mediators are related to indications watched early in patients with sepsis. In spite of

decades of investigation, the morbidity and mortality of sepsis stay exceptionally very

high. Regardless of the recognition of numerous prospective targets in the complex

immune response pathways, no specific immunotherapeutic medicines are at present

accessible. Presently, immunosuppression in sepsis is a subject matter of strong

research amongst various pre-clinical and clinical studies. In fact, an improved

consideration of a patient’s immune status on a constant basis will plausibly allow

focused immunotherapy. This book chapter provides an overview of the epidemiology,

etiology, pathogenesis of sepsis and gives an outline of the challenges in

immunotherapy for patients suffering from sepsis.

Keywords: Immunotherapy, Inflammatory, Sepsis, Septic shock.

Cite as

Current Drug Safety

Inflammation & Allergy - Drug Targets (Discontinued)

Recent Patents on Anti-Infective Drug Discovery

Current Drug Discovery Technologies

Current Drug Targets - Inflammation & Allergy

Current Bioactive Compounds

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Anti-Cancer Agents in Medicinal Chemistry

Current Drug Targets

Letters in Drug Design & Discovery

A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems

Advances in Cancer Drug Targets

Angiogenesis & Therapeutic Targets In Cancer

Anti-Angiogenesis Drug Discovery and Development

DOI https://doi.org/10.2174/9789815036879122110007	Print ISSN 1574-0889
Publisher Name Bentham Science Publisher	Online ISSN 2212-1064

Frontiers in Drug Design and Discovery