Abstract
Transcription factors are key regulators of the pattern of gene expression in a cell and directly control central processes such as proliferation, survival, self-renewal, and invasion. Alterations in the mechanisms that normally control these functions can lead to hematological malignancies. This chapter will describe the highlights of the main transcription factors in hematological malignancies.
Keywords: Hypoxia-Inducible Factors (HIF-1), Nuclear Factor-κB (NF-κB), Signal Transducer and Activator of Transcription (STAT), Homeobox (HOX), Lymphoma, Myelodysplastic Syndromes, Leukemia, NUP98-HOXA9, Multiple Myeloma, Therapeutic Strategies.
Related Journals
Current Dentistry
Current Traditional Medicine
Adolescent Psychiatry
New Emirates Medical Journal
Current Radiopharmaceuticals
Recent Patents on Anti-Cancer Drug Discovery
Current Medicinal Chemistry - Anti-Cancer Agents
Current Cancer Therapy Reviews
Clinical Cancer Drugs
Anti-Cancer Agents in Medicinal Chemistry
Related Books
Andrology: Current and Future Developments
Male Infertility: An Integrative Manual of Western and Chinese Medicine
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Recent Advances in Anesthesiology
Awake Thoracic Surgery
The Anatomical Foundations of Regional Anesthesia and Acute Pain Medicine Macroanatomy Microanatomy Sonoanatomy Functional anatomy
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents