Introduction of Nanoparticles in Medicine

Nanotechnology is a branch of science that deals with nanomaterials with a size of less than 100nm. These nanoparticles have a wide variety of applications in the field of bioimaging, biosensors, drug delivery, gene therapy, etc. The main advantage of using nanoparticles is that they may be fabricated as desired depending upon the area of application. The size, surface chemistry and physiochemical properties may be changed as required by following the parameters of synthesis. Nanoparticles may also help in RNAi therapy that delivers siRNA, shRNA and miRNAs to the target site. The major drawback of using these RNA molecules in their bare form is the fragile nature that makes them degradable by the enzymes in the blood vascular system. In this regard, nanoparticles protect them from degradation as they may encapsulate the RNA molecules within their structure. There are mainly three types of nanoparticles such as inorganic, organic and polymeric nanoparticles. In this book, we are intended to discuss the wide variety of nanoparticles that are used in biosensing, bioimaging, drug delivery, gene therapy, immunotherapy and vaccination.

Keywords: Bioimaging, Biological property, Biosensor, Chemical property, DNA, Electronic property, Immunotherapy, MiRNA, Nanocarrier, Nanomaterial, Nanomedicine, Nanotechnology, Nanoparticle, Optical property, Physical property, RNAi therapy, ShRNA, SiRNA, Theranostic, Vaccine.