An Introduction to Neurodegenerative Diseases and its Treatment

In the 21st century, a lot of progress has been made in the treatment against different kinds of Neurodegenerative disorders (NDs). Antioxidant therapy is one of the most common types of therapy for NDs. Among Antioxidant therapy, reduced GSH delivery systems are widely utilized. Gut-microbiome based treatment is also widely accepted. The blood-brain barrier (BBB) is one of the major hurdles that reduce the efficacy of several neuroprotective drugs. That is why nanoformulation based drug is currently trending to potentially treat the neurodegenerative disease. 3D organoid model is employed to mimic the in vivo condition for the development of drugs for NDs. Target specific surgical interventions are also utilized to improve the symptoms of neurological diseases. Chemical compound mediated protection only provides symptomatic relief. In long term usage, this chemical compound causes several side effects. Herbal plant-mediated therapy is a better alternative for the same. Diet is a basic part of our life. By manipulating our diet in such a way that include several beans may be very helpful in the treatment of several NDs. Accordingly, this chapter explores some important recent advancement in the treatment of different NDs.

Keywords: Alzheimer`s disease, Huntington`s disease, Mucuna pruriens, Parkinson`s disease, Ursolic acid.