Abstract
[4+2] Cycloadditions between “in situ” generated α,α-dioxothiones and unprotected or variously protected glycals provide a powerful synthetic way to obtain glycomimetics chemo-, regio- and stereoselectively. Examples of glycopeptidomimetics and mimetic of tumor antigens are reported.
Keywords: Hetero Diels-Alder, mimetics, tumor antigens, glycopeptides, matrix metalloproteinases
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Cite this chapter as:
Cristina Nativi, Elisa Dragoni, Barbara Richichi, Stefano Roelens ;Diels-Alder Based Synthesis of Glycomimetics, Synthesis and Biological Applications of Glycoconjugates (2011) 1: 240. https://doi.org/10.2174/978160805277611101010240
DOI https://doi.org/10.2174/978160805277611101010240 |
Publisher Name Bentham Science Publisher |