Post-Transplant Diabetes Mellitus: Evaluation and Management

Pp: 54-77 (24)

* (Excluding Mailing and Handling)

Abstract

Diabetes mellitus affects up to 50% of renal transplant recipients. The incidence of hyperglycemia is high in the early transplant period due to surgery and the exposure to immunosuppressant medications. Patients who develop post-transplant diabetes mellitus (PTDM) are at increased risk of cardiovascular events, infections, graft loss, and mortality. Pre- and post-transplant screening is essential for early detection and management of individuals at high risk for PTDM. This chapter aims to review the latest evidence on the epidemiology, risk factors, guidance on screening, management of the disease and its complications. New international consensus guidelines on diagnosis, current research, as well as quality improvement options will be discussed.

Keywords: Calcineurin inhibitors, Immunosuppressive agents, Incidence, Management of post-transplant diabetes mellitus, Modifiable and non-modifiable risk factors, Pathophysiology of post-transplant diabetes mellitus, Post-transplant diabetes mellitus, Post-transplant screening, Pre-transplant screening, Prevalence, Renal transplant.