Abstract
The combination of bleeding control strategies associated with lifestyle modifications, gentle physical activity, and the eventual use of ortheses are the basic principles to prevent the haemophilic arthropathy in its severe stages that represent the most common clinical manifestation of Haemophilia. Several conservative treatments may be also useful. Intraarticular injections of hyaluronic acid (viscosupplementation), Rifampicine (chemical synoviorthesis), and radioactive colloids (radiosynoviorthesis) with their different indications have been associated with good results. Other approaches as platelet-rich-plasma injections or synovial endovascular embolization have still to be validated and understood to ensure their safety or effectiveness.
Keywords: Chemical synoviorthesis, Endovascular embolization, Haemophilia, Haemophilic arthropathy, Hyaluronic acid, Platetet rich plasma, Physical synoviorthesis rifampicine Radiocolloids, Viscosupplementation.