Frontiers in Arthritis

Volume: 1

Role of Cartilage Regeneration in the Management of Early Knee Arthritis: Current Concepts

Author(s): Mark F. Sommerfeldt, Avijit Sharma and David C. Flanigan

Pp: 70-90 (21)

DOI: 10.2174/9781681083513117010011

* (Excluding Mailing and Handling)

Abstract

In this chapter, we discuss review cartilage restoration surgery in the setting of early knee osteoarthritis (OA). We introduce an algorithmic approach to determining treatment and discuss procedures including microfracture, autologous matrix-induced chondrogenesis (AMIC®), osteochondral autograft transfer (OATS), osteochondral allografting (OCA), autologous chondrocyte implantation (ACI)/matrixassisted chondrocyte implantation (MACI), and stem cell therapy. These techniques have particular advantages and disadvantages. The authors share their approach and outline the protocol for postoperative rehabilitation.


Keywords: ACI, AMIC, Cartilage, MACI, Microfracture, OATS, OCA, Osteoarthritis, Rehabilitation, Stem cell therapy.

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