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Letters in Organic Chemistry

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ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

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Research Article

Choline Chloride: Zinc Chloride Ionic Liquid Mediated Inverse Electron Demand (IED) Diels-Alder Reaction; An eco-benign Synthesis of Pyranoquinolines and Furanoquinolines

Author(s): Palani Amudha, Gnanamani Lavanya, Karuppan Venkatapathy and Chinnian Jayaraman Magesh*

Volume 16, Issue 11, 2019

Page: [865 - 873] Pages: 9

DOI: 10.2174/1570178616666190118152927

Price: $65

Abstract

A recyclable, eco-friendly, efficient method of synthesis has been developed for the biologically active heterocycles pyranoquinolines and furanoquinolines via inverse electron demand Diels- Alder reaction mediated by choline chloride: zinc chloride ionic liquid as a catalyst and medium. The methodology offers the advantages such as mild reaction conditions, simple work-up procedure, highly efficient reaction, recyclable and eco-friendly catalyst etc. All the products were thoroughly characterized by FT-IR, 1H-NMR, 13C-NMR, Mass spectral and Elemental analysis.

Keywords: Imine, substituted aldehydes, inverse electron demand diels-alder reaction, ionic liquid (choline chloride, zinc chloride), pyranoquinolines.

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