[1]
Marti, A.; Martinez-González, M.A.; Martinez, J.A. Interaction between genes and lifestyle factors on obesity. Proc. Nutr. Soc., 2008, 67(1), 1-8.
[2]
Kelly, T.; Yang, W.; Chen, C.S.; Reynolds, K. Global burden of obesity in and projections to 2030. Int. J. Obes., 2008, 32(9), 1431-1437.
[3]
World Health Organization (WHO) Prevalence of obesity and overweight worldwide. World health. Statistics, 2010.
[4]
Patel, A.V.; Hildebrand, J.S.; Gapstur, S.M. Body mass index and all-cause mortality in a large prospective cohort of white and black US adults. PLoS One, 2014, 9(10)e109153
[5]
Anjana, R.M.; Pradeepa, R.; Deepa, M.; Datta, M.; Sudha, V.; Unnikrishnan, R.; Bhansali, A.; Joshi, S.R.; Joshi, P.P.; Yajnik, C.S.; Dhandhania, V.K.; Nath, L.M.; Das, A.K.; Rao, P.V.; Madhu, S.V. Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India: Phase I results of the Indian Council of Medical Research-India DIABetes (ICMR-INDIAB) study. Diabetologia, 2011, 54(12), 3022-3027.
[6]
O’Rahilly, S.; Barroso, J.; Wareham, N.J. Genetic factors in type 2 diabetes: The end of the beginnings? Sci, 2005, 307(5708), 370-373.
[7]
Katz, A.; Nambi, S.S.; Mather, K.; Baron, A.D.; Follmann, D.A.; Sullivan, G.; Quon, M.J. Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans. J. Clin. Endocrinol. Metab., 2000, 85(7), 2402-2410.
[8]
Saldaña-Alvarez, Y.; Salas-Martínez, M.G.; García-Ortiz, H. Gender-dependent association of FTO polymorphisms with body mass index in Mexicans.Wang G, ed PLoS On; , 2016, 11, p. (1)e0145984.
[9]
Frayling, T.M.; Timpson, N.J.; Weedon, M.N.; Zeggini, E.; Freathy, R.M.; Lindgren, C.M.; Perry, J.R.; Elliott, K.S.; Lango, H.; Rayner, N.W.; Shields, B. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Sci, 2007, 316(5826), 889-894.
[10]
Larder, R.M.M.; Cheung, Y.L.; Tung-Yeo, G.S.; Coll, A.P. Where to go with FTO? Trends Endocrinol. Metabol., 2011, 22(2), 53-59.
[11]
Jia, G.; Yang, C.G.; Yang, S.; Jian, X.; Yi, C.; Zhou, Z.; He, C. Oxidative demethylation of 3- methylthymineand 3-methyluracil in single-strandeed DNA and RNA by mouse and human FTO. FEBS Lett., 2008, 582, 3313-3319.
[12]
Gerken, T.; Girard, C.A.; Tung, Y.C.; Webby, C.J.; Saudek, V.; Hewitson, K.S. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Sci., 2007, 318(5855), 1469-1472.
[13]
Stratigopoulos, G.; Padilla, S.L.; LeDuc, C.A.; Watson, E.; Hattersley, A.T.; McCarthy, M.I. Regulation of Fto/Ftm gene expression in mice and humans. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2008, 294(4), 1185-1196.
[14]
Fischer, J.; Koch, L.; Emmerling, C.; Vierkotten, J.; Peters, T.; Bruning, J.C.; Ruther, U. Inactivation of the FTO gene protects from obesity. Nat., 2009, 458(7240), 894-988.
[15]
Poritsanos, N.J.; Lew, P.S.; Fischer, J.; Mobbs, C.V.; Nagy, J.I.; Wong, D.; Rüther, U.; Mizuno, T.M. Impaired hypothalamic FTO expression in response to fasting and glucose in obese mice. Nutr. Diabetes, 2011, 1e19
[16]
Church, C.; Moir, L.; McMurray, F.; Girard, C. Banks, G.T.; Teboul, L.; Wells, S.; Brüning, J.C.; Nolan, P.M.; Ashcroft, F.M.; Cox, R.D. Over expression of FTO leads to increased food intake and results in obesity. Nat. Genet., 2010, 42(12), 1086-1092.
[17]
Ehrlich, A.C.; Friedenberg, F.K. Genetic associations of obesity: The fat mass and obesity-associated (FTO) gene. Clin. Transl. Gastroenterol., 2016, 7e140
[18]
Srivastava, A.; Srivastava, N.; Mittal, B. Genetics of obesity. Indian J. Clin. Biochem., 2016, 31(4), 361-371.
[19]
Asfaw, A. The effects of obesity on doctor-diagnosed chronic diseases in Africa: Empirical results from Senegal and South Africa. J. Public Health Policy, 2006, 27(3), 250-264.
[20]
Ellabany, E.M. Abel-Nasser. Community Based Survey Study on Non Communicable Diseases and their Risk Factors. Egypt, 2005- 2006. Tech. Rep Egypt Ministry of Health and Population, and WHO, 2006.
[21]
Tawe, L.; Zoe, N.G.; Veerapen, N.K.; Yap, R.W.; Hon, W.M.; Lim, R. Association of FTO17817449 variant with obesity and the energy intake and physical activity parameters in Malaysian adolescents. J. Biochem. Mol. Biol., 2016, 1, 16-23.
[22]
Tomei, S.; Mamtani, R.; Ali, R.; Elkum, N.; Abdulmalik, M.; Ismail, A.; Cheema, I.; Hani, F.; Al-Samraye, S.; Taher Aseel, M.; El Emadi, N.; Al Mujalli, A. Obesity susceptibility loci in Qataris, a highly consanguineous Arabian population. J. Transl. Med., 2015, 13(
119), 0459-0463.
[23]
Kumar, S.; Raju, M.; Gowda, N. Influence of parental obesity on school children. Indian J. Pediatr., 2010, 77, 256-361.
[24]
Alami, F.M.; Ahmadi, M.; Bazrafshan, H.; Tabarraei, A.; Khosravi, A. Association of the TCF7L2rs12255372(G/T) variant with type 2 diabetes mellitus in an Iranian population. Genet. Mol. Biol., 2012, 35, 413-417.
[25]
Hansson, O.; Zhou, Y.; Renstrom, E. Osmark. Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes mellitus. Curr. Diab. Rep., 2010, 10(6), 444-451.
[26]
Wing, M.R.; Ziegler, J.M.; Langefeld, C.D.; Roh, B.H.; Palmer, N.D.; Mayer-Davis, E.J.; Rewers, M.J.; Haffner, S.M.; Wagenknecht, L.E.; Bowden, D.W. Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort. Int. J. Obes., 2011, 35(9), 1173-1182.
[27]
Prakash, J.; Srivastava, N. Awasthi, S. Agarwal, C.G.; Natu, S.M.; Rajpal, N.; Mittal, B. Association of FTO rs17817449 SNP with obesity and associated physiological parameters in a north Indian population. Ann. Hum. Biol., 2011, 38(6), 760-763.
[28]
Lombard, Z.; Crowther, N.J.; van der Merwe, L.; Pitamber, P.; Norris, S.; Ramsay, M. Appetite regulation genes are associated with body mass index in black South African adolescents: A genetic association study. BMJ Open, 2012, 2e000873
[29]
Bradfield, J. Taal. H.; Rob, Timpson, N.J.; Scherag, A.; Lecoeur, C.; Warrington, N.M. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat. Genet., 2012, 44(5), 526-531.
[30]
Albuquerque, D.; Nóbrega, C.; Manco, L. Association of FTO polymorphisms with obesity and obesity-related outcomes in Portuguese children. PloS One, 2013, 8(1)e54370
[31]
Guclu-Geyik, F.; Onat, A.; Yuzbasıogulları, A.B.; Coban, N.; Can, G.; Lehtimäki, T.; Erginel-Unaltuna, N. Risk of obesity and metabolic syndrome associated with FTO gene variants discloses clinically relevant gender difference among Turks. Mol. Biol. Rep., 2016, 43(6), 485-494.
[32]
Lappalainen, T.; Kolehmainen, M.; Schwab, U.S.; Tolppanen, A.M.; Stancakova, A. Lindstorm, J.; Eriksson, J.G.; Keinänen-Kiukaanniemi, S.; Aunola, S.; Ilanne-Parikka, P. Herder, C.; Koenig, W.; Gylling, H. Kolb, H.; Tuomilehto, J. Kuusisto, J.; Uusitupa, M. Association of the FTO gene variant(rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - the Finish Diabetes Prevention Study. Nutr. Metab. Cardiovasc. Dis., 2011, 21(9), 691-698.
[33]
Do, R. Bailey, S.D.; Desbiens, K.; Belisle, A.; Montpetit, A. Bouchard, C.; Pérusse, L.; Vohl, M.C.; Engert, J.C. Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. Diabetes, 2008, 57(4), 1147-1150.
[34]
Ibba, A.; Pilia, S.; Zavattari, P. Loche, S. The role of FTO genotype on eating behavior in obese Sardinian children and adolescents. J. Pediatr. Endocrinol. Metabol., 2013, 26(5-6), 539-544.
[35]
Abadi, A. Peralta -Romero, J.; Suarez, F.; Gomez- Zamudio, J.; Buguete- Garcia, A.I.; Cruz, M.; Mayer, D. Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children. Obesity , 2016, 24(9), 1989-1995.
[36]
Hofker, M.; Wijmenga, C.A. Supersized list of obesity genes. Nat. Genes, 2009, 41(2), 139-140.
[37]
Speakman, J.R. The ‘fat mass and obesity related’ (FTO) gene: Mechanisms of impact on obesity and energy balance. Curr. Obes. Rep., 2015, 4(1), 73-91.
[38]
Kilpelainen, T.O.; Zhu, J.; Liu, C.; Yang, Z.; Zhang, Z.; Bao, W.; Cha, Y.; Wu, T.; Yang, A.; Sekine, B.Y.; Choi, C.S.; Yajnik, D.; Zhou, F.; Takeuchi, K.; Yamamoto, J.C.; Chan, K.; Mani, R. Association of genetic variation in FTO with the risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologica, 2012, 55(4), 981-995.
[39]
Abbasi, A.; Juszczyk, D.; Jaarsveld, C.; Gulliford, M. Body mass index and incident type 1 and type 2 diabetes in children and young adults: A retrospective cohort study. J. Endocr. Soc., 2017, 1(5), 524-537.
26
2