[1]
Altekruse SF, Henley SJ, Cucinelli JE, McGlynn KA. Changing hepatocellular carcinoma incidence and liver cancer mortality rates in the United States. Am J Gastroenterol 2014; 109(4): 542-53.
[2]
Duan XY, Zhang L, Fan JG, Qiao L. NAFLD leads to liver cancer: do we have sufficient evidence? Cancer Lett 2014; 345(2): 230-4.
[3]
Pang Q, Qu K, Zhang J, et al. Cigarette smoking increases the risk of mortality from liver cancer: A clinical-based cohort and meta-analysis. J Gastroenterol Hepatol 2015; 30(10): 1450-60.
[4]
Amberger JS, Bocchini CA, Schiettecatte F, Scott AF, Hamosh A. OMIM.org: Online Mendelian Inheritance in Man (OMIM(R)), an online catalog of human genes and genetic disorders. Nucleic Acids Res 2015; 43(Database issue): D789-98.
[5]
Wu G, Wilson G, George J, Qiao L. Modulation of Notch signaling as a therapeutic approach for liver cancer. Curr Gene Ther 2015; 15(2): 171-81.
[6]
Song B, Bian Q, Shao CH, et al. Ulinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagy. PLoS One 2015; 10(3): e0120694.
[7]
Nio K, Yamashita T, Okada H, et al. Defeating EpCAM + liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma. J Hepatol 2015; 63(5): 1164-72.
[8]
Vilchez V, Turcios L, Marti F, Gedaly R. Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment. World J Gastroenterol 2016; 22(2): 823.
[9]
Carbajopescador S, Mauriz JL. FoxO proteins: regulation and molecular targets in liver cancer. Curr Med Chem 2014; 21(10): 1231-46.
[10]
Mollinedo F, Gajate C. Lipid rafts as major platforms for signaling regulation in cancer. Adv Biol Regul 2015; 57: 130-46.
[11]
Hryniewicz-Jankowska A, Augoff K, Biernatowska A, Podkalicka J, Sikorski AF. Membrane rafts as a novel target in cancer therapy. Biochim Biophys Acta 2014; 1845(2): 155-65.
[12]
Ma DW. Lipid mediators in membrane rafts are important determinants of human health and disease. Appl Physiol Nutr Metab 2007; 32(3): 341.
[13]
Kun-Peng Z, Xiao-Long M, Chun-Lin Z. LncRNA FENDRR sensitizes doxorubicin-resistance of osteosarcoma cells through down-regulating ABCB1 and ABCC1. Oncotarget 2017; 8(42): 71881-93.
[14]
Xu TP, Huang MD, Xia R, et al. Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expression. J Hematol Oncol 2014; 7(1): 63.
[15]
Xiong Q, Wu S, Wang J, et al. Hepatitis B virus promotes cancer cell migration by downregulating miR-340-5p expression to induce STAT3 overexpression.%A Xiong Q. Cell Biosci 2017; 7: 16.
[16]
Gao B, Wang H, Lafdil F, Feng D. STAT proteins - key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver. J Hepatol 2012; 57(2): 430-41.
[17]
Wilson CL, Jurk D, Fullard N, et al. NF[kappa]B1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun 2015; 6: 8411.
[18]
Cheng CW, Su JL, Lin CW, et al. Effects of NFKB1 and NFKBIA gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathological features. PLoS One 2013; 8(2): e56130.
[19]
Kuo KK, Lee KT, Chen KK, et al. Positive feedback loop of OCT4 and c-JUN expedites cancer stemness in liver cancer. Stem Cells 2016; 34(11): 2613-24.
[20]
Moles A, Butterworth JA, Sanchez A, et al. A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer. Oncogene 2016; 35(35): 4623-32.
[21]
Moles A, Sanchez AM, Banks PS, et al. Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. Hepatology 2013; 57(2): 817-28.
[22]
Hu B, Sun M, Liu J, Hong G, Lin Q. The preventative effect of Akt knockout on liver cancer through modulating NF-κB-regulated inflammation and Bad-related apoptosis signaling pathway. Int J Oncol 2016; 48(4): 1467-76.
[23]
Watanabe T, Suzuki T, Natsume M, et al. Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR. Mutat Res 2012; 747(2): 164-75.
[24]
Sun H, Gao Y, Lu K, et al. Overexpression of Klotho suppresses liver cancer progression and induces cell apoptosis by negatively regulating wnt/β-catenin signaling pathway. World J Surg Oncol 2015; 13(1): 307.
[25]
Melão A, Spit M, Cardoso BA, Barata JT. Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity. Haematologica 2016; 101(11): 1368-79.
[26]
Wang Z, Zhang H, Zhou J, et al. Eriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycle. Cancer Chemother Pharmacol 2016; 78(6): 1-8.
[27]
Moon H, Ju HL, Chung SI, et al. Transforming Growth Factor-β Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail. Gastroenterology 2017; 153(5): 1378.
[28]
Lazaris A, Amri A, Petrillo SK, et al. Vascularization of colorectal carcinoma liver metastasis: Insight into stratification of patients for anti-ngiogenic therapies. J Pathol Clin Res 2018; 4(3): 184-92.
[29]
Richter K, Paakkola T, Mennerich D, et al. USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner. Mol Cancer Res 2018; 16(6): 1000-12.
[30]
Liu XL, Ding J, Meng LH. Oncogene-induced senescence: a double edged sword in cancer. Acta Pharmacol Sin 2018; 39(10): 1553-8.
[31]
Huo S, Yu H, Li C, Zhang J, Liu T. Effect of halofuginone on the inhibition of proliferation and invasion of hepatocellular carcinoma HepG2 cell line. Int J Clin Exp Pathol 2015; 8(12): 15863.
[32]
Bhardwaj A, Sethi G, Vadhan-Raj S, et al. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood 2007; 109(6): 2293-302.
[33]
Qiang D, Xia Y, Ding S, Lu P, Liang S, Mei L. An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9. Oncotarget 2016; 7(12): 14405-14.
[34]
Szklarczyk D, Franceschini A, Wyder S, et al. STRING v10: protein-protein interaction networks, integrated over the tree of life.%A Szklarczyk D. Nucleic Acids Res 2015; 43(Database issue): D447-52.
[35]
Katarzyna T, Patrycja C, Maciej W. The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge. Contemp Oncol (Pozn) 2015; 19(1A): 68-77.
[36]
Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 2008; 9(1): 559.
[37]
Zhang Y, Fan H, Xu J, et al. Network analysis reveals functional cross-links between disease and inflammation genes. Sci Rep 2013; 3: 3426.
[38]
Artzy-Randrup Y, Fleishman SJ, Ben-Tal N, Stone L. Comment on “Network motifs: simple building blocks of complex networks” and “Superfamilies of evolved and designed networks”. Science 2004; 305(5687): 1107.
[39]
Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 2003; 13(11): 2498.
[40]
Yi Y, Zhao Y, Li C, et al. RAID v2.0: an updated resource of RNA-associated interactions across organisms. Nucleic Acids Res 2017; 45(D1): D115-8.
[41]
Han H, Cho JW, Lee S, et al. TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions. Nucleic Acids Res 2018; 46(D1): D380-6.
[42]
Liu N, Li C, Huang Y, et al. A functional module-based exploration between inflammation and cancer in esophagus. Sci Rep 2015; 5: 15340.
[43]
Yu G, Wang LG, Han Y, He QY. clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters. OMICS 2012; 16(5): 284-7.
[44]
Maere S, Heymans K, Kuiper M. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 2005; 21(16): 3448-9.
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