Nano Copper Catalyzed Microwave Assisted Coupling of Benzene Boronic Acids with Thiophenols

Title:Nano Copper Catalyzed Microwave Assisted Coupling of Benzene Boronic Acids with Thiophenols

Volume: 16 Issue: 6

Author(s): Dinesh S. Gavhane, Aniket P. Sarkate*, Kshipra S. Karnik, Shritesh D. Jagtap, Sajed H. Ansari, Ashwini V. Izankar, Ishudeep K. Narula, Vaishnavi S. Jambhorkar and Aishwarya P. Rajhans

Affiliation:

• Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, 431004 (MS),India

Keywords: Microwave assisted, S-arylation, C-S bond, CuFe2O4 nanoparticles, conventional heating, ligand free.

Abstract: A proficient, microwave mediated methodology using CuFe2O4 nanoparticle as the catalyst for S-arylation of substituted benzene boronic acids with thiophenol has been developed. In this method, the substituted thioethers were easily obtained through a C-S bond formation using microwave irradiation technique as well as conventional heating in the presence of CuFe2O4 nanoparticles with modest to excellent yields with the less reaction time. The ligand free microwave technique helped in the preparation of substituted thioethers in measurable amount within 10 mins. The same results were obtained with conventional heating in 12h. The reported method is economically efficient and an alternative to the initial existing method for the preparation of substituted thioethers.

Cite this article as:

Gavhane S. Dinesh , Sarkate P. Aniket *, Karnik S. Kshipra , Jagtap D. Shritesh , Ansari H. Sajed , Izankar V. Ashwini , Narula K. Ishudeep , Jambhorkar S. Vaishnavi and Rajhans P. Aishwarya , Nano Copper Catalyzed Microwave Assisted Coupling of Benzene Boronic Acids with Thiophenols, Letters in Organic Chemistry 2019; 16 (6) . https://dx.doi.org/10.2174/1570178616666181116113243