Abstract
Although, numerous antimicrobial agents have been reported by the scientists to control fungal and bacterial diseases, but due to less cost effectiveness, non-availability and environmental hazardous of existing antimicrobial agents, there is still a need to synthesize new class of antimicrobial agents to control microbes effectively. Coumarin, a heterocyclic compound containing oxygen in its scaffold, acts as a building block for large number of biologically active compounds and is known to possess variety of biological activities viz. antiviral, antimicrobial, anticonvulsant, anticancer analgesic and antiinflammatory. This review mainly focuses on various methods related to synthesis of coumarin derivatives and its biological activity as antimicrobial.
Keywords: Coumarin, heterocyclic, antimicrobial, antibacterial, antifungal, microbe.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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