Abstract
Inflammatory Bowel Diseases (IBD) are now widely receiving attention. There are many reasons why people get IBD; for example, environment, smoking, family heredity, intestinal microbiota and so on. Antibiotics have not been proven effective and those suffering from IBD have begun to look for other effective drugs to treat the chronic disease. Bioactive peptides are a good candidate among alternative drugs tested so far, and have been seen to control bodily growth, development, immune regulation and metabolism. This paper will review the literature describing the effects of bioactive peptides on intestinal inflammation. Studies conducted using in vivo models and clinical trials provide evidence that bioactive peptides can be effective in mitigating intestinal inflammation.
Keywords: Inflammatory bowel diseases, bioactive peptide, intestinal microbiota, defensins, chronic disease, antibiotics.
Current Pharmaceutical Design
Title:Effects of Bioactive Peptide on Inflammatory Bowel Disease, Focus on Signal Transduction and Intestinal Microbiota
Volume: 24 Issue: 24
Author(s): Yong Ma, Wenxin Yan, Sujuan Ding, Yanquan Fei, Gang Liu* Jun Fang*
Affiliation:
- College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, Hunan 410128,China
- College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, Hunan 410128,China
Keywords: Inflammatory bowel diseases, bioactive peptide, intestinal microbiota, defensins, chronic disease, antibiotics.
Abstract: Inflammatory Bowel Diseases (IBD) are now widely receiving attention. There are many reasons why people get IBD; for example, environment, smoking, family heredity, intestinal microbiota and so on. Antibiotics have not been proven effective and those suffering from IBD have begun to look for other effective drugs to treat the chronic disease. Bioactive peptides are a good candidate among alternative drugs tested so far, and have been seen to control bodily growth, development, immune regulation and metabolism. This paper will review the literature describing the effects of bioactive peptides on intestinal inflammation. Studies conducted using in vivo models and clinical trials provide evidence that bioactive peptides can be effective in mitigating intestinal inflammation.
Export Options
About this article
Cite this article as:
Ma Yong, Yan Wenxin , Ding Sujuan , Fei Yanquan , Liu Gang *, Fang Jun *, Effects of Bioactive Peptide on Inflammatory Bowel Disease, Focus on Signal Transduction and Intestinal Microbiota, Current Pharmaceutical Design 2018; 24 (24) . https://dx.doi.org/10.2174/1381612824666180829103945
DOI https://dx.doi.org/10.2174/1381612824666180829103945 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
GnRH Agonists and Antagonists in Cancer Therapy
Current Medicinal Chemistry - Anti-Cancer Agents Collagen-Binding Integrins as Pharmaceutical Targets
Current Pharmaceutical Design Single Amino Acid Repeats Connect Viruses to Neurodegeneration
Current Drug Discovery Technologies Immune Therapy for Infectious Diseases at the Dawn of the 21st Century: the Past, Present and Future Role of Antibody Therapy, Therapeutic Vaccination and Biological Response Modifiers
Current Pharmaceutical Design Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications
Current Organic Chemistry Adenovirus Vectors for Gene Therapy, Vaccination and Cancer Gene Therapy
Current Gene Therapy Therapeutic Biology of Jatropha curcas: A Mini Review
Current Pharmaceutical Biotechnology Anti-inflammatory Effects of Mesenchymal Stem Cells and their Secretomes in Pneumonia
Current Pharmaceutical Biotechnology The Offer of Chemistry to Targeted Therapy in Cancer
Recent Patents on Biotechnology Sphere Formation Assay is not an Effective Method for Cancer Stem Cell Derivation and Characterization from the Caco-2 Colorectal Cell Line
Current Stem Cell Research & Therapy Structure-Function Relationship of Thiazolides, a Novel Class of Anti-Parasitic Drugs, Investigated in Intracellular and Extracellular Protozoan Parasites and Larval-Stage Cestodes
Anti-Infective Agents in Medicinal Chemistry Activin Receptor-Like Kinases: Structure, Function and Clinical Implications
Endocrine, Metabolic & Immune Disorders - Drug Targets Pathophysiology of Diabetic Dyslipidaemia
Current Vascular Pharmacology Definition of Markov-Harary Invariants and Review of Classic Topological Indices and Databases in Biology, Parasitology, Technology,and Social-Legal Networks
Current Bioinformatics Inflammation-Mediating Proteases: Structure, Function in (Patho) Physiology and Inhibition
Protein & Peptide Letters Sumoylation Plays Fundamental Roles During Eye Development and Pathogenesis
Current Molecular Medicine The Function of the Selective Inhibitors of Cycloxygenase 2
Mini-Reviews in Medicinal Chemistry Cancer Biomarker Discovery for Precision Medicine: New Progress
Current Medicinal Chemistry MMP14 Regulates VEGFR3 Expression on Corneal Epithelial Cells
Protein & Peptide Letters Recent Progress and Related Patents on the Applications of Bone Marrow-Derived Stem/Progenitor Cells in Regenerative Medicine and Cancer Therapies
Recent Patents on Regenerative Medicine