摘要
背景:阿尔茨海默病痴呆患者的表达困难已被广泛研究,主要是在口语方面。然而,他们写作过程的恶化受到的关注却要少得多。目的:本研究旨在探讨阿尔茨海默病患者在口头和笔画命名任务中的表现下降情况。方法:将64名受试者(一半为阿尔茨海默病患者,另一半为健康老年人)在图片命名任务的口头和书面版本中进行比较。随访时间为两年半,每半年对患者进行一次评估。结果:横断面数据显示,对照组的表现优于患者,两组均表现出不同的错误类型。在纵向数据方面,结果显示两项任务的恶化模式相似。在错误方面,词汇语义学在开始时是最多的,在所有评价中,它们的数量保持不变。在没有答复的情况下,在最后一次会议上,口头和书面命名都有了显著的增加。结论:这些结果复制了以前的研究结果,并突出了命名任务在发现阿尔茨海默病患者进化过程中的微小变化方面的作用。
关键词: 阿尔茨海默病,图片命名,失范,书写障碍,认知衰退,纵向研究。
Current Alzheimer Research
Title:Oral and Written Naming in Alzheimer’s Disease: A Longitudinal Study
Volume: 15 Issue: 12
关键词: 阿尔茨海默病,图片命名,失范,书写障碍,认知衰退,纵向研究。
摘要: Background: The expressive difficulties in patients with Alzheimer’s dementia have been extensively studied, mainly in oral language. However, the deterioration of their writing processes has received much less attention.
Objective: The present study aims to examine the decline of the performance of patients with Alzheimer’s disease in both oral and written picture-naming tasks.
Method: Sixty-four participants (half with Alzheimer’s disease and half healthy elderly) were compared in the oral and written versions of a picture-naming task. Follow-up lasted two and a half years and patients were evaluated every six months.
Results: Cross-sectional data indicate that the controls performed better than the patients, and both groups showed a different pattern of errors. In terms of longitudinal data, the results show a similar pattern of deterioration in both tasks. In terms of errors, lexical-semantics were the most numerous at the beginning and their number remained constant throughout all evaluations. In the case of non-responses, there was a significant increase in the last session, both in oral and written naming.
Conclusion: These results replicate those found in previous studies and highlight the utility of the naming task to detect minimal changes in the evolution of patients with Alzheimer’s disease.
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Cite this article as:
Oral and Written Naming in Alzheimer’s Disease: A Longitudinal Study, Current Alzheimer Research 2018; 15 (12) . https://dx.doi.org/10.2174/1567205015666180813145402
DOI https://dx.doi.org/10.2174/1567205015666180813145402 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
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