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Review Article

自然漫步：倍半萜烯内酯作为多靶点药物参与炎症途径

卷 27, 期 9, 2020

页: [1501 - 1514] 页: 14

弟呕挨: 10.2174/0929867325666180719111123

价格: $65

摘要

炎症状态是最常见和治疗最多的疾病之一。使用患处时，炎症伴随肿胀，疼痛和不适感。炎症并不总是一个简单的症状。通常是身体对外部威胁的防御反应的一部分，或者是受损组织尚未愈合且需要休息的迹象。处理与炎症状态相关的疼痛可能是一项艰巨的任务。实际上，大多数疗法仅能止痛，而不会改变炎症状态。这篇综述集中在倍半萜内酯，一类天然化合物，代表了炎症治疗的未来前景。倍半萜内酯是炎性过程的多个靶标的有效抑制剂。它们的天然来源通常是古老的药物，在民间医学中具有相关的传统用途。这项工作还旨在阐明这些化合物如何代表开发新的消炎药的起始材料。

关键词: 倍半萜内酯，炎症，NF-κB，MAPK，COX-2，消炎药，天然化合物。

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