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Review Article

抗肿瘤作用金属纳米粒子的研究进展 - 综述

卷 26, 期 12, 2019

页: [2108 - 2146] 页: 39

弟呕挨: 10.2174/0929867325666180214102918

价格: $65

摘要

癌症一词代表一组100多种由于细胞不受控制的生长引起的疾病;它们随后通过一种称为“转移”的现象扩散到身体的其他组织和器官。根据世界卫生组织（WHO）提供的估计，预计到2020年癌症每年约有1000万人死亡，2100万癌症病例，到2030年可导致1300万人死亡，使癌症成为原因。与其他疾病相比，死亡率最高。寻求可能减少由于癌细胞和正常细胞之间识别困难而发生的副作用的抗癌治疗药物的需求一直在增加。在这种观点中，纳米技术，特别是金属纳米颗粒（MNPs），有助于开发新的治疗剂，其可以用最多样化的功能化学基团合成或修饰;该性质使得金属纳米颗粒适合与已知药物或预期候选药物缀合。生物相容性，相对简单的合成，尺寸灵活性和易于化学修饰的表面，都使得金属纳米颗粒非常有利于癌症的适当诊断和治疗。本文分析和报道了78种不同金属纳米粒子的纸张的抗肿瘤活性，特别是含有铜，金，铁，银和钛的金属纳米粒子。

关键词: 金属纳米粒子，纳米技术，抗肿瘤活性，铜，金，铁，银，钛。

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