Abstract
Depression is a common psychiatric disorder and a leading cause of disability worldwide. Traditional Chinese medicine is one of the commonly used complementary and alternative medicine therapies for depression. Clinical trials have been carried out to assess the efficacy and safety of Chinese herbal medicine currently. The exploration of herbal mechanisms of action used for the treatment of depression has also received great attention. This study is performed to summarize the frequently used formulae, patent drugs and single herbs in treating depression, review the literatures of clinical trials in treating depressive disorders, and to list the possible mechanisms involved during the treatment. Besides, we will analyze the limitations of present studies and the obstacles in the modernization of traditional Chinese medicine.
Keywords: Depression, traditional Chinese medicine, clinical trials, therapeutic mechanisms, modernization, review.
Current Pharmaceutical Design
Title:Chinese Herbal Medicine for the Treatment of Depression: Applications, Efficacies and Mechanisms
Volume: 23 Issue: 34
Author(s): Yuanyuan Wang, Menglin Li, Yan Liang, Yiting Yang, Zhe Liu, Keyu Yao, Zijie Chen and Shuangqing Zhai*
Affiliation:
- School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing 100029,China
Keywords: Depression, traditional Chinese medicine, clinical trials, therapeutic mechanisms, modernization, review.
Abstract: Depression is a common psychiatric disorder and a leading cause of disability worldwide. Traditional Chinese medicine is one of the commonly used complementary and alternative medicine therapies for depression. Clinical trials have been carried out to assess the efficacy and safety of Chinese herbal medicine currently. The exploration of herbal mechanisms of action used for the treatment of depression has also received great attention. This study is performed to summarize the frequently used formulae, patent drugs and single herbs in treating depression, review the literatures of clinical trials in treating depressive disorders, and to list the possible mechanisms involved during the treatment. Besides, we will analyze the limitations of present studies and the obstacles in the modernization of traditional Chinese medicine.
Export Options
About this article
Cite this article as:
Wang Yuanyuan , Li Menglin , Liang Yan , Yang Yiting , Liu Zhe , Yao Keyu , Chen Zijie and Zhai Shuangqing *, Chinese Herbal Medicine for the Treatment of Depression: Applications, Efficacies and Mechanisms, Current Pharmaceutical Design 2017; 23 (34) . https://dx.doi.org/10.2174/1381612823666170918120018
DOI https://dx.doi.org/10.2174/1381612823666170918120018 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Vascular and Cardiac Oxidative Stress and Inflammation as Targets for Cardioprotection
Current Pharmaceutical Design Important Hints in Behavioural Teratology of Rodents
Current Pharmaceutical Design Recent Advances in Therapy of Schizophrenia
Current Psychiatry Reviews PPARs in Neurodegenerative and Neuroinflammatory Pathways
Current Alzheimer Research MCI Patients Declining and Not-Declining at Mid-Term Follow-Up: FDG-PET Findings
Current Alzheimer Research Association and Causal Relationship of Midlife Obesity and Related Metabolic Disorders with Old Age Cognition
Current Alzheimer Research Pharmacological Approaches to Targeting Muscarinic Acetylcholine Receptors
Recent Patents on CNS Drug Discovery (Discontinued) Genetic Predisposition to Parkinson’s Disease and Cancer
Current Cancer Drug Targets Recent Advances in Prion Chemotherapeutics
Infectious Disorders - Drug Targets Fullerene-like Nanoparticles of Titanium Disulfide
Current Nanoscience Graphical Abstracts:
Current Neuropharmacology Neurovascular Changes in Acute, sub-Acute and Chronic Mouse Models of Parkinson’s Disease
Current Neurovascular Research The Effect of a Spiritual Care on Hope in Patients Undergoing Hemodialysis: A Randomized Controlled Trial
Current Psychiatry Research and Reviews “European Panel on Low Density Lipoprotein (LDL) Subclasses”: A Statement on the Pathophysiology, Atherogenicity and Clinical Significance of LDL Subclasses
Current Vascular Pharmacology Virulence Factors of Helicobacter pylori: Practical Biomarkers
Recent Patents on Biomarkers Amyloid β Conformation in Aqueous Environment
Current Alzheimer Research Applications of Barton-McCombie Reaction in Total Syntheses
Current Organic Synthesis Osteoporosis Entwined with Cardiovascular Disease: The Implication of Osteoprotegerin and the Example of Statins
Current Medicinal Chemistry M2000, Foundation of a New Generation Among NSAIDs
Letters in Drug Design & Discovery Editorial [ Hot Topic: Drugs Targets in Parkinson's Disease:Where Are We and Where should We Go? (Guest Editor: Mark R. Cookson)]
CNS & Neurological Disorders - Drug Targets