摘要
环状二肽是自然界中常见的最简单的肽衍生物。 这些手性分子可以使用简单的方法从容易获得的α-氨基酸容易地合成。 它们是具有结合多种受体并具有广泛种类的生物和药理活性的特殊结构。 我们将简要介绍一下他们的状态给出和有趣的参考列表关于最后的作品。
关键词: 环状二肽,次生代谢物,生物活性,二酮哌嗪,环(L-pro),天然化合物。
Current Medicinal Chemistry
Title:Cyclic Dipeptides: Secondary Metabolites Isolated from Different Microorganisms with Diverse Biological Activities
Volume: 24 Issue: 25
关键词: 环状二肽,次生代谢物,生物活性,二酮哌嗪,环(L-pro),天然化合物。
摘要: Cyclic dipeptides are the simplest peptide derivatives commonly found in nature. These chiral molecules are easily synthesized from readily available α-amino acids using a simple methodology. They are privileged structures with the ability to bind to a wide range of receptors and have a broad variety of biological and pharmacological activities. We will give a brief overview of their status giving and interesting reference list about the last works.
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Cite this article as:
Cyclic Dipeptides: Secondary Metabolites Isolated from Different Microorganisms with Diverse Biological Activities, Current Medicinal Chemistry 2017; 24 (25) . https://dx.doi.org/10.2174/0929867324666170623092818
DOI https://dx.doi.org/10.2174/0929867324666170623092818 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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