摘要
与物质使用障碍相关的记忆，或与物质相关的线索，会增加戒断期间渴望和复发的可能性。越来越多的人认为，突触可塑性的操纵可能会降低与滥用物质有关的记忆的强度。在生物学方面，有新的见解表明，与物质使用障碍相关的记忆可能遵循独特的神经生物学途径，使它们更容易被药理学干预。与此同时，神经化学的研究已经发现了几个可能影响长期记忆形成和维持的候选分子。靶向这些分子的药物(blebbistatin, isradipine和zeta抑制性肽)在临床前阶段已经显示出希望。在这篇综述中，我们将概述对记忆形成所涉及的生化机制的不断发展的理解，并阐述物质使用障碍是一种学习障碍的前提。
关键词: 成瘾，记忆，复发，提示，白比司他汀，异地平，PKM Zeta。
图形摘要
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