摘要
目的：痴呆症患者的在休息晚间的临床问题和夜间兴奋昼夜活动节律紊乱问题已经达到了极点，本研究的目的是测试动态照明系统对痴呆患者的兴奋和休息活动周期的影响。 方法：从冬至起，一个正在安装的天花板上的动态照明系统被安装在一个疗养院的公共休息室，白天生产高亮度的蓝光，在晚上没有蓝光，且照度更低。15个有痴呆症的居民患有规律地通过科恩曼斯菲尔德搅拌指数（CMAI）前、后照明干预进行评估。此外，休息活动周期通过手腕佩戴活动手表连续监测6个月。CMAI数据分析采用Wilcoxon秩和检验进行配对（安装照明前与安装照明后）。休息活动的数据与相依样本通过t检验进行比较。动态照明显著降低CMAI总分数从30.2±5.1 到 27.9±2.6 (mean ± SD; N = 12; p<0.05)。CMAI评分的分析表明，动态照明下主要是非物理攻击行为减少。 结果：静息活动分析结果显示照明前后的昼夜节律和其他昼夜节律变量差异不明显。在起居室动态照明能显著降低痴呆患者不安行为，表明较高的日光暴露有着短期效益。这种照明是否影响长期（昼夜）休息活动周期还需要进一步研究。
关键词: 不安、昼夜节律、痴呆、灯、灯光治疗、疗养院、休息活动模式
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