摘要
目的：我们通过在严重痴呆症患者的情绪、激越行为、生活质量、褪黑素分泌和昼夜活动周期方面来测试一个动态的照明系统的效果是否优于传统照明系统。作为对照，年龄匹配的对照组患者暴露于常规照明下。在秋季/冬季的8个研究星期中，两个光照条件的差异没有显著的差异。 方法：首先，我们将病人（n = 89）分成两组，仅根据他们每天的个人光暴露的中位数。平均每日光照（417勒克斯）的患者每日观察的快感和警觉性明显高于每日轻度暴露的患者。此外，他们有更高的生活质量，花更少的时间在床上，后来上床睡觉，并开始他们的睡眠后，即使两组没有不同的年龄，认知功能障碍和流动性的严重程度。一般来说，男人更容易不安，睡眠更短，唤醒时间更多，有一个较低的相对静止唤醒活动的昼夜节律振幅和进入白天的昼夜稳定性高于女性。特别是，较低的每日光照显著地预测了男性静息活动周期的较低幅度，但在女性中却没有预测到。这可能表明老年痴呆患者中对日常休息活动的调节曝光易感性有一定的性别特异性。
关键词: 精神病人、老年痴呆、动态照明、情感、性别差异、日光、昼夜。
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