Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases

Title:Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases

Volume: 23 Issue: 41

Author(s): Swathi Putta, Nagendra S. Yarla*, Ilaria Peluso, Dinesh K. Tiwari, Gorla V. Reddy, Priyanka V. Giri, Naresh Kumar, Ramarao Malla, Vijaya Rachel, P. Veera Bramhachari, Rama S. Reddy D, Ramesh Bade, Mastan Mannarapu, George E. Barreto, Da-Yong Lu, Vadim V. Tarasov, Vladimir N. Chubarev, Frederico F. Ribeiro, Luciana Scotti*, Marcus T. Scotti, M.A. Kamal, Ghulam Md Ashraf, Gjumrakch Aliev, George Perry, Satyajit D. Sarker, Chinthalapally V. Rao and Anupam Bishayee

Affiliation:

• Institute of Science, GITAM University, Visakhapatnam-530045, A.P,India

• Federal University of Paraiba, Campus I, 58051-970, Joao Pessoa, PB,Brazil

Keywords: Anthocyanins, multitarget therapeutic agents, antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory and anticarcinogenic activity.

Abstract: Anthocyanins, a flavonoid class of polyphenols, are water soluble dark colored natural pigments found in fruits and vegetables. Owing to their wide distribution in plant materials, dietary consumption of anthocyanins is high compared to other flavonoids. Anthocyanins, due to their multifaceted medicinal properties are the active components in many herbal folk medicines. As in vitro and in vivo results, animal models, and clinical trials in various cell lines suggest, anthocyanins possess antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, anticarcinogenic, antiulcer, and preventive activities against cardiovascular diseases. Additionally, anthocyanins exhibit chemotherapeutic, cardioprotective, hepatoprotective, and neuroprotective activities. In the diet, anthocyanins are absorbed in the stomach and intestinal cells and rapidly detected in the plasma. These promising properties of anthocyanins may well provide health benefits against chronic diseases.

Cite this article as:

Putta Swathi , Yarla S. Nagendra *, Peluso Ilaria , Tiwari K. Dinesh , Reddy V. Gorla, Giri V. Priyanka , Kumar Naresh , Malla Ramarao , Rachel Vijaya , Bramhachari Veera P. , Reddy D S. Rama , Bade Ramesh, Mannarapu Mastan , Barreto E. George , Lu Da-Yong, Tarasov V. Vadim , Chubarev N. Vladimir , Ribeiro F. Frederico , Scotti Luciana *, Scotti T. Marcus, Kamal M.A., Ashraf Md Ghulam , Aliev Gjumrakch, Perry George , Sarker D. Satyajit , Rao V. Chinthalapally and Bishayee Anupam , Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases, Current Pharmaceutical Design 2017; 23 (41) . https://dx.doi.org/10.2174/1381612823666170519151801