Abstract
The perpetuation of healthy vision is paramount in an individual. It has been observed that various drug delivery systems have been fabricated to develop vision quality in individuals. Systemic ocular drug therapies have limited efficacy due to poor bioavailability, systemic and toxic side effects and low patient compliance. Various drug systems which follow the ocular route of administration are manufactured to achieve optimized bioavailability along with better patient compliance. Ocular implant is one such example. It is divided into biodegradable and non-biodegradable drug delivery systems wherein the former is more beneficial. This review aims to demonstrate the current momentum in the formulation and optimization of various biodegradable ocular drug delivery systems and its characteristics.
Keywords: Biodegradable polymers, biodegradable implants, advancements, pharmaceutical technology, ocular implants, bioavailability.
Graphical Abstract
Current Drug Delivery
Title:Recent Advancemnts in Biodegradable Ocular Implants
Volume: 15 Issue: 2
Author(s): Swati Mittal and Oshin Miranda*
Affiliation:
- Department of Pharmacology, University of Minnesota (Medical School Twin cities), Minnesota, 55455,United States
Keywords: Biodegradable polymers, biodegradable implants, advancements, pharmaceutical technology, ocular implants, bioavailability.
Abstract: The perpetuation of healthy vision is paramount in an individual. It has been observed that various drug delivery systems have been fabricated to develop vision quality in individuals. Systemic ocular drug therapies have limited efficacy due to poor bioavailability, systemic and toxic side effects and low patient compliance. Various drug systems which follow the ocular route of administration are manufactured to achieve optimized bioavailability along with better patient compliance. Ocular implant is one such example. It is divided into biodegradable and non-biodegradable drug delivery systems wherein the former is more beneficial. This review aims to demonstrate the current momentum in the formulation and optimization of various biodegradable ocular drug delivery systems and its characteristics.
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Cite this article as:
Mittal Swati and Miranda Oshin *, Recent Advancemnts in Biodegradable Ocular Implants, Current Drug Delivery 2018; 15 (2) . https://dx.doi.org/10.2174/1567201814666170508104254
DOI https://dx.doi.org/10.2174/1567201814666170508104254 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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