Non-conventional Green Strategies for NHC Catalyzed Carbon-Carbon Coupling Reactions

Title:Non-conventional Green Strategies for NHC Catalyzed Carbon-Carbon Coupling Reactions

Volume: 21 Issue: 22

Author(s): Majid M. Heravi*, Bahareh Heidari, Mahdieh Ghavidel and Tahereh Ahmadi

Affiliation:

• Department of Chemistry, School of Sciences, Alzahra University, Vanak, Tehran,Iran

Keywords: Cross-Coupling Reactions, N-Heterocyclic Carbene (NHC), green chemistry, microwave irradiation, aqueous media, Pdcatalyzed reaction, suzuki reaction, heck reaction.

Abstract: Background: Coupling reactions, commonly can be achieved via a wide range of organometallic reagents and electrophiles, representing an important class of synthetic transformation, namely “cross-coupling reaction. It is frequently catalyzed by various palladium (Pd) as species. The synthesis and characterization of an N-heterocyclic carbine (NHC) was accomplished in 1991. In 1991, the first synthesis of a stable NHC was achieved and reported.

Objective: This development literally invigorated the interest and attention for this novel species being examined as a ligand for the synthesis of Pd Complexes.

Conclusion: In this review, we tried to give a full account on the development of NHC–Pd chemistry intended being used as catalyst under non-conventional conditions. In this light, those carbon-carbon bond formations being successfully achieved in aqueous systems, using immobilized NHC-Pd complexes under nonconventional strategies, such as being conducted under microwave irradiations (MWI) are supported and solvent- free conditions are discussed.

Cite this article as:

Heravi M. Majid *, Heidari Bahareh, Ghavidel Mahdieh and Ahmadi Tahereh, Non-conventional Green Strategies for NHC Catalyzed Carbon-Carbon Coupling Reactions, Current Organic Chemistry 2017; 21 (22) . https://dx.doi.org/10.2174/1385272821666170410103712