摘要
背景：维生素D在胃肠道生物学和病理生理学中的效应机制的生物医学文献正在迅速扩大。因此，正在鉴定维生素D生物学治疗性干预胃肠疾病的新可能性。然而，文献缺乏对这些发展的简要回顾，妨碍了解社区中的人类所涉及的可能性。 结果：遗传维生素D受体（VDR）多态性以及其他VDR生物学调节涉及胃肠癌的倾向，并且可能允许用于管理那些特别是处于危险中的个体的策略，例如通过维生素D进行膳食补充。此外，通过维生素D类似物调节刺猬信号可能有利于对抗胃肠癌或改善IBD中的屏障功能，但维生素D水平可能也会通过与粘膜免疫系统的作用而影响肠胃中的炎症条件。有证据证明维生素D维持状态的监测正在积累。 结论：维生素D生物学与胃肠道生物学的血多方面有千变万化的相互作用，维生素D似乎是精确和P4药物等个性化方法的有吸引力的目标。
关键词: 消化通路生理，万花筒，胃肠道，生理学，维生素D，维生素D受体
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