Abstract
In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths worldwide. This article reviews advances in the treatment of this pathology using several types of nanoparticles. First, we start with an overview of gastric cancer, its prevention, detection and the available treatments. Then, we discuss nanotechnology-based novel strategies using polymeric nanosystems, nanovesicular systems and inorganic nanoparticles. All of these systems are being evaluated in the perspective of improving the targeting of anticancer drugs and reducing their negative side effects.
Keywords: Nanoparticles, nanocarriers, gastric cancer, treatment, drug delivery, targeting.
Current Pharmaceutical Design
Title:Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy
Volume: 22 Issue: 39
Author(s): Ariel R. Guerrero, Felipe Oyarzun-Ampuero, Natalia Hassan, Alejandro H. Corvalan, Andrew F.G. Quest and Marcelo J. Kogan
Affiliation:
Keywords: Nanoparticles, nanocarriers, gastric cancer, treatment, drug delivery, targeting.
Abstract: In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths worldwide. This article reviews advances in the treatment of this pathology using several types of nanoparticles. First, we start with an overview of gastric cancer, its prevention, detection and the available treatments. Then, we discuss nanotechnology-based novel strategies using polymeric nanosystems, nanovesicular systems and inorganic nanoparticles. All of these systems are being evaluated in the perspective of improving the targeting of anticancer drugs and reducing their negative side effects.
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Cite this article as:
Guerrero R. Ariel, Oyarzun-Ampuero Felipe, Hassan Natalia, Corvalan H. Alejandro, Quest F.G. Andrew and Kogan J. Marcelo, Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy, Current Pharmaceutical Design 2016; 22 (39) . https://dx.doi.org/10.2174/1381612822666160712165409
DOI https://dx.doi.org/10.2174/1381612822666160712165409 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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