上呼吸道一氧化氮的研究进展

Title:Recent Advances on Nitric Oxide in the Upper Airways

Volume: 23 Issue: 24

Author(s): Mauro Maniscalco, Andrea Bianco, Gennaro Mazzarella, Andrea Motta

Affiliation:

关键词: 哮喘、炎症、哼唱、PCD、鼻息肉、鼻、鼻窦炎

摘要: Exhaled nitric oxide (NO) originates from the upper airways, and takes action, to varying extents, in regulation, protection and defense, as well as in noxious processes. Nitric oxide retains important functions in a wide range of physiological and pathophysiological processes of the human body, including vaso-regulation, antimicrobial activity, neurotransmission and respiration. This review article reports the ongoing investigations regarding the source, biology and relevance of NO within upper respiratory tract. In addition, we discuss the role of NO, originating from nasal and paranasal sinuses, in inflammatory disorders such as allergic rhinitis, sinusitis, primary ciliary dyskinesia, and cystic fibrosis.

Cite this article as:

Mauro Maniscalco, Andrea Bianco, Gennaro Mazzarella, Andrea Motta , Recent Advances on Nitric Oxide in the Upper Airways, Current Medicinal Chemistry 2016; 23 (24) . https://dx.doi.org/10.2174/0929867323666160627115335