Abstract
Currently, dendrimers are molecules widely investigated due to their strong potential for biomedical (including diagnostic, drug discovery, and drug delivery platforms) and others applications. The requirements demanded by Food and Drug Administration (FDA) of a new drug application involve several analytical techniques for characterization, which allow understanding the properties of the novel platforms, and to predict their interactions with the biological environment. This work proposes a full description to perform the analytical characterization of dendrimers, including techniques for evaluating the morphology, shape, molecular weight, polydispersity, and purity; as well as methods for the synthesize and conjugation with molecules for targeting.
Keywords: Dendrimers, NMR, mass spectrometry, spectroscopy, differential scanning, rheology, scattering techniques, microscopy.
Graphical Abstract
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
21
2