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Nanoscience & Nanotechnology-Asia

Editor-in-Chief

ISSN (Print): 2210-6812
ISSN (Online): 2210-6820

Review Article

Potential Application of Silver Nanoparticles in Medicine

Author(s): Kanav Midha, Garima Singh, Manju Nagpal and Sandeep Arora

Volume 6, Issue 2, 2016

Page: [82 - 91] Pages: 10

DOI: 10.2174/2210681205666150818230319

Price: $65

Abstract

Nanoparticles offer targeted delivery of drugs, enhancing bioavailability, sustaining drug or gene effect in target tissues, and enhancing the stability. Silver nanoparticles have played a main role in the field of nanotechnology and nanomedicine. Silver nanoparticles (AgNPs) (1-100 nm in size) are produced by chemical reduction from silver nitrate using different organic compounds (Tri-ethyl-amine, Alpha-Terpineol) and organic bases (as reaction promoter). Plant extracts of Carob plant and Rumex hymenosepalu plant have also been used for the synthesis. These are made up of large amount of silver oxide due to huge ratio of surface to bulk silver atoms. Silver ions have been normally used in medicine and biology for years, but silver particles altered with nano-technological methods offers new possibilities. Silver nanoparticles account for greater than 23% of all nanoproducts and have been widely used for diagnostic and therapeutic applications (e.g. in wound healing, arthritic disease, etc.). These have been widely known for their antibacterial, antifungal, and antiviral effects. Nanosilver form has been applied in various advanced technological applications (e.g. conductive coatings). These are also employed in textile fabrics, added into cosmetic products as antiseptic as well as preservative to treat dermal problems. Thus, Silver nanoparticles (AgNPs) have been developed as a superior product in the field of nanotechnology.

Keywords: Antibacterial effect, atomic absorption spectroscopy, green synthesis, nanosilver, silver nitrate.

Graphical Abstract


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