Abstract
In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.
Keywords: Functionalized nucleosides, modified nucleosides, fluorinated nucleosides, selenonucleosides, thionucleosides, biologically active nucleosides.
Graphical Abstract
Current Organic Chemistry
Title:Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities
Volume: 20 Issue: 8
Author(s): Sarbjit Singh, Deepak Bhattarai, Gajulapati Veeraswamy, Yongseok Choi and Kyeong Lee
Affiliation:
Keywords: Functionalized nucleosides, modified nucleosides, fluorinated nucleosides, selenonucleosides, thionucleosides, biologically active nucleosides.
Abstract: In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.
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Cite this article as:
Singh Sarbjit, Bhattarai Deepak, Veeraswamy Gajulapati, Choi Yongseok and Lee Kyeong, Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities, Current Organic Chemistry 2016; 20 (8) . https://dx.doi.org/10.2174/1385272819666150803235458
DOI https://dx.doi.org/10.2174/1385272819666150803235458 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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